Sökning: "intracerebroventricular ICV"

Hittade 5 avhandlingar innehållade orden intracerebroventricular ICV.

  1. 1. Insulin-like Growth Factor-I (IGF-I) and Interleukin-6 (IL-6) regulate body fat

    Författare :Kristina Wallenius; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; insulin-like growth factor I IGF-I ; interleukin-6 IL-6 ; growth hormone GH ; GH releasing factor GHRF ; GH secretagogue GHS ; receptor; leptin; insulin; glucose; intracerebroventricular ICV ; dual-energy X-ray absorptiometry DXA ; indirect calorimetry.;

    Sammanfattning : The aim of this thesis was to investigate the role of insulin-like growth factor-I (IGF-I) and interleukin-6 (IL-6) in the regulation of metabolism and body fat mass. Circulating IGF-I is mainly liver derived, while a large part of circulating IL-6 is produced by adipose tissue. LÄS MER

  3. 2. Roles of Arginine-Vasotocin and Corticotropin-Releasing Hormone in Stress Responses and Agonistic Behaviour of Rainbow Trout

    Författare :Tobias Backström; Svante Winberg; Lynne Sneddon; Uppsala universitet; []
    Nyckelord :Zoophysiology; arginine-vasotocin AVT ; corticotropin releasing hormone CRH ; stress; stress coping; behaviour; rainbow trout; Zoofysiologi;

    Sammanfattning : The neuropeptides arginine-vasotocin (AVT) and corticotropin-releasing hormone (CRH) are involved in the hypothalamic-pituitary-interrenal (HPI) axis. During stress, the HPI axis is activated and cortisol is released into the blood. In addition to their role in the HPI axis, AVT and CRH also have behavioural effects. LÄS MER

  4. 3. Bridging immune activation with the kynurenine pathway : implications for psychosis

    Författare :Markus Larsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Kynurenic acid (KYNA), an endogenous N-Methyl-D-aspartic acid receptor (NMDAR) antagonist, is elevated in patients with schizophrenia. In addition, elevated levels of KYNA are associated with activation of the immune system, which also has been implicated in the development and maintenance of psychotic disorders, including schizophrenia. LÄS MER

  5. 4. Experimental models for investigating IAPP regulation of food intake in rats and mice

    Författare :Madelene Olsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :adiposity;

    Sammanfattning : Background: Maintenance of energy balance is one of the fundamental processes of living organisms and involves complex regulatory pathways. Appetite regulation is an important component of this, because it modulates energy intake. LÄS MER

  7. 5. Modeling disturbances of cholinergic systems : possible relevance for schizophrenia

    Författare :Anna Mattsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cholinergic; nucleus basalis; 192 IgG-saporin; schizophrenia; locomotor activity; dopamine; microdialysis; memory; MRI;

    Sammanfattning : Schizophrenia is a severe, chronic mental disorder. The etiology remains unknown but alterations in cholinergic neurotransmission is one, among other, disturbances in the brain that have been implicated in schizophrenia. LÄS MER