Sökning: "intracellular sorting"
Visar resultat 11 - 15 av 30 avhandlingar innehållade orden intracellular sorting.
11. Biogenesis of tartrate-resistant acid phosphatase isoforms 5a and 5b in cell and animal models
Sammanfattning : Tartrate-resistant acid phosphatase (TRAP) is an iron-containing binuclear acid metallohydrolase that belongs to the purple acid phosphatase (PAP) family. It is a glycoprotein translated as a monomeric protein but is commonly isolated from tissues as a proteolytically processed dimeric form with increased enzyme activity. LÄS MER
12. Mechanisms for Targeting of Proteins to Secretory Lysosomes of Haematopoietic Cells
Sammanfattning : The cells of the innate immune system are essential for the host's first line defence against infection. Among these cells the neutrophil granulocyte has a central role by the production of antibiotic proteins and peptides. LÄS MER
13. Structure and function of the HDL receptor SR-BI : scavenger receptor class B type I
Sammanfattning : Low plasma levels of high-density lipoprotein (HDL) and high levels of low-density lipoprotein (LDL) are well-recognized risk factors for cardiovascular disease. The uptake and degradation of LDL cholesterol have been characterized in detail at the molecular level. Less is known about the metabolism and cellular uptake of HDL cholesterol. LÄS MER
14. Dual Targeting of Proteins to Mitochondria and Chloroplasts
Sammanfattning : The vast majority of mitochondrial and chloroplastic proteins are nuclear encoded, synthesized in the cytosol and imported into the respective organelle using an N-terminal extension, the targeting peptide (TP). After import into the organelle, the TP is cleaved off and degraded by the Presequence protease (PreP). LÄS MER
15. Structural Details of Human Aquaporin Regulation : Three stories of three aquaporins
Sammanfattning : Every cell is surrounded by a thin plasma membrane, protecting it from its surrounding. Specialized protein channels and transporters are embedded in this membrane, ensuring selective transport of molecules in and out of the cells. To maintain optimal hydration, water channels called aquaporins (AQPs) are present in every cell of our body. LÄS MER