Sökning: "intracellular diffusion"

Visar resultat 1 - 5 av 37 avhandlingar innehållade orden intracellular diffusion.

1. 1. Measuring Material Properties through Gradient Based NMR: Diffusion and Imaging

   Författare :Ingrid Åslund; Fysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; intracellular diffusion; homogeneous length-scale; material properties; emulsions; yeast suspensions; lamellar phase; NMR; self-diffusion; membrane permeability and bending rigidity;

   Sammanfattning : In this work new methods based Nuclear Magnetic Resonance (NMR) have been developed to measure different kinds of structural properties in soft materials. The advantage of using NMR as a technique to measure material properties is that it is non-destructive, which makes it possible to measure on the actual piece of material that will be used for the application. LÄS MER

3. 2. Translational Tumor Drug Delivery : Doxorubicin formulation performance, intracellular uptake and molecular diffusion

   Författare :Oliver Degerstedt; Hans Lennernäs; Erik Sjögren; Per Hansson; Jessica Rosenholm; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; doxorubicin; drug diffusion; cellular uptake; drug delivery; PBPK modelling; hepatocellular carcinoma; emulsion; IC50; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : Globally, hepatocellular carcinoma (HCC) is the most common form of liver cancer and a leading cause of cancer death. One important risk factor is liver cirrhosis and the disease progression is characterized by deposition of extracellular matrix proteins that form a fibrous network, which increases liver stiffness and may limit the effectiveness of different treatment strategies. LÄS MER

4. 3. Intracellular Flows and Fluctuations

   Författare :Johan Elf; Måns Ehrenberg; Peter Wolynes; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; mesoscopic; reaction-diffusion; protein synthesis; amino acid; flow; fluctuations; Molekylärbiologi; Molecular biology; Molekylärbiologi; Molecular Biotechnology; Molekylär bioteknik;

   Sammanfattning : Mathematical models are now gaining in importance for descriptions of biological processes. In this thesis, such models have been used to identify and analyze principles that govern bacterial protein synthesis under amino acid limitation. LÄS MER

5. 4. On boundary value problems for intracellular subdiffusion and signaling pathways, and for geometric flows

   Författare :Tobias Gebäck; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; boundary value problems; diffusion-reaction equations; signaling pathways; anomalous diffusion; pseudo-differential equations; fluorescence correlation spectroscopy; immersed interface method; Boolean grids; mean curvature flow; pseudo-differential equations; boundary value problams; flourescence correlation spectroscopy;

   Sammanfattning : The main part of this thesis concerns mathematical models for diffusion of proteins inside cells, including reactions between the proteins. Initially, such models are applied to describe signaling pathways in yeast cells, and the properties of the model are studied, especially in relation to models that do not include diffusion. LÄS MER

7. 5. Biological Insights from Single-Particle Tracking in Living Cells

   Författare :Arash Sanamrad; Johan Elf; Måns Ehrenberg; Achillefs Kapanidis; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; single-particle tracking; intracellular diffusion; nucleoid exclusion; transcription-translation coupling; antibiotics; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

   Sammanfattning : Single-particle tracking is a technique that allows for quantitative analysis of the localization and movement of particles. In this technique, trajectories are constructed by determining and connecting the positions of individual particles from consecutive images. LÄS MER