Sökning: "intracellular calcium"

Visar resultat 16 - 20 av 195 avhandlingar innehållade orden intracellular calcium.

  1. 16. Intracellular calcium movements in glucose-stimulated pancreatic ß-cells

    Författare :Tommy Andersson; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 17. NMR studies on calcium-induced conformational transitions in calmodulin

    Författare :Johan Evenäs; Biofysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; NMR; conformational exchange; calmodulin; calcium binding; Fysikalisk kemi;

    Sammanfattning : Nuclear magnetic resonance (NMR) spectroscopy was used in order to investigate the relationships between structure, dynamics and calcium binding in the intracellular regulatory protein, calmodulin. Calmodulin consists of two similar domains, each binding two calcium ions with positive cooperativity. LÄS MER

  4. 18. Engineering alternative scaffold proteins for conditional targeting

    Författare :Malin Jönsson; Sophia Hober; Mark Howarth; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Protein Engineering; Conditional targeting; Calcium; Biotechnology; Bioteknologi;

    Sammanfattning : Engineering naturally occurring proteins enables us to customize affinity domains according to our specific needs, tailoring them to become an important tool in a wide array of applications limited merely by our creativity. One of nature’s ways to regulate protein activity is by creating a functional change through alteration of a protein’s tertiary structure upon interaction with metal ions. LÄS MER

  5. 19. Mechanochemical Modeling of Smooth Muscle Activation

    Författare :Sae-Il Murtada; Gerhard A. Holzapfel; Robert McMeeking; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biomechanics; Muscle contraction; Smooth muscle; Contractile unit; Filament overlap; Intracellular calcium; Carotid artery; Mathematical model;

    Sammanfattning : Smooth muscle has an important role in several physiological processes, where it regulates the wall tension and the size of hollow organs. In blood vessels, the contraction and relaxation of smooth muscle contribute to the mechanical stability of the vessel wall and determines the diameter. LÄS MER

  7. 20. The Duodenal Mucosal Bicarbonate Secretion : Role of Melatonin in Neurohumoral Control and Cellular Signaling

    Författare :Markus Sjöblom; Gunnar Flemström; Olof Nylander; Karl EO Åkerman; Per M. Hellström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; alkaline secretion; central nervous system; duodenal enterocyte; duodenal ulcer; duodenum; enterochromaffin cell; human; intraarterial; intracellular calcium; intracerebroventricular; melatonin; rat; vagal nerve; Fysiologi; Physiology; Fysiologi;

    Sammanfattning : The duodenal lumen is exposed to aggressive factors with a high potential to cause damage to the mucosa. Bicarbonate secretion by the duodenal mucosa is accepted as the primary important defense mechanism against the hydrochloric acid intermittently expelled from the stomach. LÄS MER