Sökning: "interstitial pneumonia"

Hittade 5 avhandlingar innehållade orden interstitial pneumonia.

  1. 1. Pulmonary tuberculosis and Pneumocystis jiroveci pneumonia in HIV-infected patients in Ethiopia

    Författare :Getachew Aderaye; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The objective of this study initially was to determine the prevalence of culture-verified pulmonary tuberculosis in TB suspects and investigate the impact of human immunodeficiency virus (HIV) infection on the prevalence, clinical and radiological presentation and diagnosis of tuberculosis. During the study, it soon became clear that the HIV sero-prevalence in tuberculosis (TB) suspects who could not be verified to be culture-positive was too high to deserve an explanation. LÄS MER

  3. 2. Infections in allogeneic stem cell transplanted patients : clinical and immunological aspects

    Författare :Elda Sparrelid; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HSCT; bacteraemia invasive fungal infection; interstitial pneumonia; immunity.;

    Sammanfattning : In allogeneic haematopoietic stem cell transplantation (HSCT), 30 to 40 % of transplant related mortality is associated with infection complications. This includes invasive bacterial and fungal infection, and interstitial pneumonia (IP), which are two important causes of morbidity and mortality. LÄS MER

  4. 3. Role of the co-transcriptional regulators Yap/Taz in the normal and fibrotic lung epithelia

    Författare :Hani N. Alsafadi; NanoLund: Centre for Nanoscience; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lung Epithelium; idiopathic pulmonary fibrosis IPF ; Developmental pathways; Hippo Signaling; Yap Taz; transcription factors; 3D culture models; ;

    Sammanfattning : Idiopathic pulmonary fibrosis (IPF) is a fatal disease that exhibits patterns of usual interstitial pneumonia with honeycombing. IPF is characterized by damaged distal lung epithelium with excessive tissue scarring and extracellular matrix remodeling. The etiology of IPF is unknown and current therapies cannot end or reverse disease progression. LÄS MER

  5. 4. Studies on mechanisms of busulphan cytotoxicity and pharmacokinetics : with special reference to liposomal busulphan

    Författare :Zuzana Hassan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Busulphan is an alkylating agent currently used in conditioning regimen prior to stem cell transplantation (SCT). High dose therapy with busulphan has been shown to contribute to transplantation-related toxicities, such as veno-occlusive disease (VOID) and interstitial pneumonia, Previous pharmacodynamic studies have attempted to define a target systemic exposure to busulphan, and thresholds for different side effects. LÄS MER

  7. 5. Cyclophosphamide and treosulfan in the conditioning regimen prior to allogeneic stem cell transplantation

    Författare :Fredrik Sjöö; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Allogeneic stem cell transplantation (SCT) is a curative treatment for malignant and non-malignant diseases. However, transplantation related morbidity and mortality are major drawbacks affecting the survival and life quality of the patients. LÄS MER