Sökning: "interstitial fluid pressure"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden interstitial fluid pressure.

  1. 1. Tumor Stroma in Anaplastic Thyroid Carcinoma : Interstitial Collagen and Tumor Interstitial Fluid Pressure

    Författare :Ellen Lammerts; Lucio Nitsch; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Collagen I synthesis; Fibrosis; Tumor - stroma interactions; PDGF; TGF-β; Inhibitor; Cell cycle; Tumor growth; Hyaluronan; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Anaplastic thyroid carcinoma (ATC) is an aggressive malignancy in man with stromal fibrosis as one of the main features. Carcinoma cells synthesized no or little collagen I protein. LÄS MER

  3. 2. Extracellular Matrix and Actin Cytoskeleton - the Control Unit of Interstitial Fluid Volume

    Författare :Vahid Reyhani; Kristofer Rubin; Markella Ponticos; Uppsala universitet; []
    Nyckelord :Collagen; fibrin; integrins; PDGF-BB; gel contraction; fluid homeostasis; interstitial fluid pressure; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : The regulation of fluid (water) volume in the body is crucial for tissue homeostasis. The interstitial fluid, which comprises almost 20% of the body fluid, is stored in the loose connective tissue and its volume is actively regulated by components of this tissue. LÄS MER

  4. 3. Taking Pressure of Anaplastic Thyroid Carcinoma : Molecular Studies of Apoptosis and Interstitial Hypertension

    Författare :Pernilla Roswall; Nils-Erik Heldin; Kristofer Rubin; Sven Påhlman; Uppsala universitet; []
    Nyckelord :Medicine; Anaplastic thyroid carcinoma; Apoptosis; Cre recombinase; 2-Methoxyestradiol; Transforming growth factor-β; Transgenic mouse; Tumor-associated macrophages; Tumor interstitial fluid pressure; Medicin;

    Sammanfattning : Molecular mechanisms in the development and progression of thyroid carcinomas are still not fully understood. In the present thesis the highly malignant anaplastic thyroid carcinoma (ATC) was used to study regulation of apoptosis and tumor interstitial fluid pressure (IFP). LÄS MER

  5. 4. Integrin αVβ3-Directed Contraction by Connective Tissue Cells : Role in Control of Interstitial Fluid Pressure and Modulation by Bacterial Proteins

    Författare :Åsa Lidén; Kristofer Rubin; Karl-Eric Magnusson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; interstitial fluid pressure; collagen gel contraction; integrin αVβ3; septic shock; fibronectin; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : This thesis aimed at studying mechanisms involved in control of tissue fluid homeostasis during inflammation.The interstitial fluid pressure (PIF) is of importance for control of tissue fluid balance. A lowering of PIF in vivo will result in a transport of fluid from the circulation into the tissue, leading to edema. LÄS MER

  7. 5. Integrated microsystems for continuous glucose monitoring, interstitial fluid sampling and digital microfluidics

    Författare :Federico Ribet; Niclas Roxhed; Göran Stemme; Boris Stoeber; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Microelectromechanical systems MEMS ; biosensors; biomedical devices; continuous glucose monitoring CGM ; glucose sensors; microneedles; interstitial fluid sampling; minimally-invasive technologies; electrochemical sensors; heterogeneous integration; wire bonding; magnetic assembly; electrowetting-on-dielectric EWOD ; digital microfluidics; ionic liquids; gas sensors; optical switches; laser shutters.; Electrical Engineering; Elektro- och systemteknik;

    Sammanfattning : Interdisciplinary research between medicine and microsystem engineering creates new possibilities to improve the quality of life of patients or to further enhance the performance of already existing devices. In particular, microsystems show great potential for the realization of biosensors and sampling devices to monitor bioanalytes with minimal patient discomfort. LÄS MER