Sökning: "internal medicine Clinical genetics Medical genetics"

Visar resultat 6 - 10 av 77 avhandlingar innehållade orden internal medicine Clinical genetics Medical genetics.

  1. 6. Monocytes, Tissue Factor and Heparin-coated Surfaces : Clinical and Experimental Studies

    Författare :Matilda Johnell; Agneta Siegbahn; Rolf Larsson; Jesper Swedenborg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; monocytes; tissue factor; heparin-coated surfaces; coagulation; inflammation; thrombin; cytokines; cardiopulmonary bypass; biocompatibility; migration; chemotaxis; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Cardiopulmonary bypass (CPB) is associated with inflammatory response and activation of coagulation. Heparin coating of the CPB circuit is shown to improve the biocompatibility of the surface. The biological effects of a new heparin surface, the Corline Heparin Surface (CHS), prepared according to a new principle, have been studied. LÄS MER

  3. 7. Metabolic aspects on diabetic nephropathy

    Författare :Maria Svensson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; invärtesmedicin; Internal Medicine;

    Sammanfattning : Diabetic nephropathy (DN) is associated with morbidity and mortality due to cardiovascular disease and renal failure. This study focused on the impact of glycemic control on the development of DN and the metabolic consequences of DN. The euglycemic hyperinsulinemic clamp technique was used to assess insulin sensitivity and insulin clearance. LÄS MER

  4. 8. CXCL16 and CD137 in atherosclerosis

    Författare :Dick Wågsäter; Allan Sirsjö; Ewa Ehrenborg; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; atherosclerosis; chemokine; cytokine; endothelial cells; inflammation; low-density lipoprotein; macrophages; scavenger receptor; smooth muscle cells; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; MEDICINE; MEDICIN; Biomedicin; Biomedicine;

    Sammanfattning : Atherosclerosis is a progressive inflammatory disease that is characterized by the accumulation of lipids, infiltrated cells and fibrous elements in large arteries. This thesis focuses on the molecular mechanisms behind foam cell formation and inflammation, two central processes in the development of atherosclerosis. LÄS MER

  5. 9. Cell Cycle Regulation in Human Renal Cell Carcinoma

    Författare :Ylva Hedberg; Göran Landberg; Börje Ljungberg; Göran Roos; Ulf Bergerheim; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Human Renal Cell Carcinoma; Cell Cycle; G1 S; Protein; Cyclin; p27; pRb; Phosphorylation; Tissue Microarray; Clinical Behaviour; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : ABSTRACTCell cycle regulation in human renal cell carcinomaYlva Hedberg, Departments of Medical Biosciences, Pathology, and Surgical andPerioperative Sciences, Urology Andrology, Umeå University, SwedenDeregulated growth control is a hallmark of neoplasia potentially caused by aberrant expression of cell cycle regulatory proteins. The importance of such aberrations in human renal cell carcinoma (RCC) has not been fully clarified. LÄS MER

  7. 10. Predictors of disease onset and progression in early rheumatoid arthritis : A clinical, laboratory and radiological study

    Författare :Ewa Berglin; Solbritt Rantapää-Dahlqvist; Thomas Skogh; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; early; rheumatoid; arthritis; anti-CCP; antibodies; factors; radiological; outcome; disease; onset; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicin; Medicine;

    Sammanfattning : To diagnose rheumatoid arthritis (RA) during the early stages of the disease is often difficult. The disease course shows great inter-individual variation from mild, self-limiting to very severe destruc-tive disease with extra-articular manifestations. LÄS MER