Sökning: "intermittent claudication"
Visar resultat 16 - 20 av 22 avhandlingar innehållade orden intermittent claudication.
16. Cardiovascular risk assessments in peripheral arterial disease : results of a ten-year follow-up of a Swedish population-based cohort
Sammanfattning : Background: An updated knowledge on natural history in Peripheral Arterial Disease (PAD) is lacking, in particular for the asymptomatic stage (APAD). The disease has strong associations with other atherosclerotic manifestations such as myocardial infarction or stroke, which could be prevented with prophylactic measures. LÄS MER
17. Chronic limb-threatening ischaemia - Prognosis after intervention
Sammanfattning : Introduction: Lower-extremity arterial disease (LEAD) is a major health problem worldwide. Chronic limb-threatening ischaemia (CLTI) is the most severe manifestation of LEAD. Open or endovascular recanalization is recommended for most patients with CLTI. LÄS MER
18. Regulatory aspects of innate immune responses
Sammanfattning : Activation of innate immunity is regulated by a variety of signaling molecules within the immune cells. The present thesis was aimed to improve our understanding of innate signaling mechanism and their possible use as bio-indicators of exposure and disease. LÄS MER
19. Blood pressure, blood pressure variability and myocardial ischemia : studies in patients with peripheral arterial disease and matched control subjects
Sammanfattning : Background: Patients presenting with peripheral arterial disease (PAD) often have concomitant coronary artery disease (CAD), which is frequently asymptomatic. Ambulatory blood pressure (ABP) monitoring improves risk stratification in hypertensive patients beyond that offered by office BP(OBP) measurements. LÄS MER
20. Identification of natural activators of the nuclear receptor peroxisome proliferator-activated receptor : relevance to the pathogenesis of atherosclerosis
Sammanfattning : Polyunsaturated fatty acids induce peroxisome proliferation. This phenomenon is mediated by the ligand-dependent transcription factor peroxisome proliferator-activated receptor (PPAR). This thesis is an investigation on the role of eicosanoids and oxidized products of linoleic acid for the activation of PPARs. LÄS MER