Sökning: "interleukin-1beta"

Visar resultat 16 - 20 av 21 avhandlingar innehållade ordet interleukin-1beta.

  1. 16. Respiratory tract infections, reflex apnea and sudden infant death : experimental and epidemiological studies with special reference to respiratory syncytial virus, Bordetella pertussis and sleep position

    Författare :Carl Lindgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Bordetella pertussis; Infection; Interleukins; Laryngeal chemoreflex; Respiratory syncytial virus; Reflex apnea; Sleep; Sleeping position; Sudden infant death;

    Sammanfattning : The seasonal distribution of Sudden infant death syndrome (SIDS) followed the prevalence of respiratory tract infections (RTI) when prone sleeping position was recommended, but this covariation has recently been attenuated. Airway infections in the young infant are known to produce respiratory disturbances. LÄS MER

  3. 17. Distribution and pathophysiological role of amyloid precursor protein and presenilin 1 : characterization in rats and in vitro studies on the pathogenic arctic mutation

    Författare :Camilla Nilsberth; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Alzheimer's disease is the most common form of dementia that presents a growing dilemma worldwide. Alzheimer's disease is neuropathologically characterized by cerebral atrophy accompanied by deposition of senile plaques and neurofibrillary tangles. LÄS MER

  4. 18. Experimental Helicobacter pylori infection in an animal model

    Författare :Yi-Qian Sun; Torkel Wadström; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Background: Helicobacter pylori is a microaerophilic Gram-negative bacterium colonizing the human stomach. The prevalence of this infection is between 20-90% depending on geographic location. Comprehensive studies have shown significant relationships between H. pylori infection and chronic gastritis, peptic ulcer and gastric carcinoma. LÄS MER

  5. 19. Studies on molecular properties and functional regulation of terminal leukotriene C4 synthases and cysteinyl-leukotriene receptor signalling in human endothelium

    Författare :Oliver Schröder; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The transformation of the unstable intermediate leukotriene (LT) A4 into the glutathione conjugate LTC4, the parent compound of LTD4 and LTE4, is catalysed by leukotriene C4 synthase (LTC4S) as well as microsomal glutathione S-transferase type 2 (MGST2) and type 3 (MGST3). Together, these eicosanoids also known as cysteinyl leukotrienes (cys-LT) are key mediators of immediate hypersensitivity reactions. LÄS MER

  7. 20. Pathological responses of glial cells in spinal cord injury and rheumatoid arthritis

    Författare :Teresa Fernández Zafra; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Scientists have considered glia as mere passive allies of neurons for a long time. As a consequence, their functions have been greatly underestimated. Major discoveries made in the last three decades have changed our view on glial cells and it is now accepted that they play important roles in health and disease. LÄS MER