Sökning: "interleukin-1beta"

Visar resultat 1 - 5 av 21 avhandlingar innehållade ordet interleukin-1beta.

1. 1. Apnea and infection in neonates : mediatory role of interleukin-1Beta and prostaglandin E2

   Författare :Annika Olsson Hofstetter; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :respiration; interleukin-1Beta; prostaglandin E2; newborns; rodents; brainstem;

   Sammanfattning : The breathing pattern of infants, particularly preterm infants, is often irregular or periodic and is frequently interrupted by apnea. The latter represents a major concern in haematology, yet much remains unknown about its incidence, appearance, and pathophysiology. LÄS MER

3. 2. Cytokine induced airway hyperreactivity characterized in an in-vitro model of asthma

   Författare :Yaping Zhang; Klinisk och experimentell allergiforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicology; Farmakologi; farmakognosi; MAPK; TNF-alpha; 5-HT; Respiratory system; Andningsorganen; Pharmacological sciences; pharmacognosy; pharmacy; interleukin-1beta; hyperresponsiveness; endothelin-1; airway; bradykinin; toxikologi; farmaci;

   Sammanfattning : Asthma is a chronic disorder of the lower airways, characterized by inflammation and hyperreactivity. Pro-inflammatory cytokines like tumour necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) are known to play important roles in the pathogenesis, but our knowledge how these cytokines contribute to the development of airway hyperreactivity is limited. LÄS MER

4. 3. Biglycan as a modulator of fibrous connective tissue

   Författare :Ellen Tufvesson; allergologi och palliativ medicin Lungmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biglycan decorin fibroblast interleukin-1beta migration proteoglycan structure tumour necrosis factor-alpha; Medicine human and vertebrates ; Medicin människa och djur ;

   Sammanfattning : Fibrous connective tissue contains fibroblasts distributed in a complex network of extracellular matrix molecules, such as proteoglycans. The small proteoglycans biglycan and decorin are composed of a protein core substituted with two and one glycosaminoglycan (GAG) chain, respectively. LÄS MER

5. 4. Effects of imidazoline compounds on intracellular CA2+ and apoptosis

   Författare :Ioulia Appelskog; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :imidazolines; imidazoline site; sulfonylurea; glucose; interleukin-1beta; insulin secretion; glucagon; somatostatin; pancreatic islets; pancreatic P-cells; HIT-T15 cells; apoptosis; cytoplasmic free Ca2 concentration;

   Sammanfattning : Cytoplasmic free Ca2+ concentration ([Ca2+]i) plays a pivotal role in the regulation of insulin release from the pancreatic beta-cell. [Ca2+]i is also important in the control of apoptosis. LÄS MER

7. 5. Staphylococcal induced inflammatory response in human monocytes: Analysis of factors involved

   Författare :Eva Mattsson; Infektionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; interleukin-6; interleukin-beta; TNF-alfa; teichoic acid; Staphylococcus epidermidis; peptidoglycan; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Sammanfattning : Purified bacterial cell wall components peptidoglycan and teichoic acid were isolated from staphylococcal species S. aureus and/or S. epidermidis and tested for their ability to induce cytokine release from plastic-adherent human monocytes. LÄS MER