Sökning: "interferon-λ"

Hittade 1 avhandling innehållade ordet interferon-λ.

1. 1. Aspects of infection and leukemia in Rwanda

   Författare :Belson Rugwizangoga; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; interferon-λ; respiratory infection; nucleotide polymorphism; acute leukemia; Rwanda; Epstein-Barr virus; malaria;

   Sammanfattning : A first part of this thesis addressed the potential impact of variants of genes encoding interferon-λ4, which is a cytokine that participates in protection against pathogens at epithelial surfaces, for the resolution of upper respiratory tract infections in Rwandan children. In a study of 480 subjects (≤5 years old), where follow-up samples were available from 161 subjects, it was observed that IFNL4 genotypes were associated with clearance of RNA viruses from upper airways. LÄS MER