Sökning: "interferon-β"

Hittade 3 avhandlingar innehållade ordet interferon-β.

  1. 1. Role of classical pro- and anti-inflammatory mediators in ischemic stroke. Beyond neuroimmunomodulation

    Författare :Ana Inacio; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; interferon-β; inflammatory immune cells; galectin-3; experimental stroke; enriched environment; cytokines; Brain; macrophage migration inhibitory factor; neuroprotection; reactive astrocytes.;

    Sammanfattning : Stroke is a leading cause of death and long-term neurological deficits worldwide, and no effective treatment is available for the vast majority of the stroke patients. A rapid and persistent activation of multiple and dynamic inflammatory and immune cascades, in and outside the brain, occurs after stroke. LÄS MER

  3. 2. Anti-CD20 therapy in multiple sclerosis : clinical and paraclinical outcomes

    Författare :Alexander Juto; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis is a chronic inflammatory disease of the central nervous system and the most common non-traumatic cause of neurological disability in young adults. Rituximab is a B-cell depleting drug targeting the CD20 epitope on B-cells, which drive inflammation in relapsing-remitting multiple sclerosis by acting as antigen-presenting cells to activate T-cell responses against central nervous system autoantigens. LÄS MER

  4. 3. Innate immune responses to a saponin adjuvant in the pig : application of gene expression profiling

    Författare :Viktor Ahlberg; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Vaccination is one of the most powerful ways to prevent infectious diseases. Successful vaccines produce a long-term immunity including effector T and B lymphocytes. In this context, adjuvants have a key role in vaccines by stimulating the innate immunity and thereby enhancing and shaping the subsequent adaptive immune response. LÄS MER