Sökning: "intercellular communication"

Visar resultat 1 - 5 av 37 avhandlingar innehållade orden intercellular communication.

  1. 1. Metabolic communication between individual yeast cells

    Författare :Martin Mojica Benavides; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Metabolic synchronization; Single-cell; glycolytic oscillations; synchronization waves;

    Sammanfattning : With the recent progress in sensitive cell manipulation and microfabrication techniques, glycolytic oscillations in yeast have been observed at a single-cell level. It was shown that individually, oscillating cells could entrain their phases by periodic external perturbations. LÄS MER

  2. 2. Intratumoral heterogeneity in glioblastoma: subtype transition and cell-to-cell communication

    Författare :Min Guo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; glioblastoma; intratumoral heterogeneity; subtype transition; intercellular communication; U-343; SOX2; SFRP2; PROX1; THRAP3; TGFBI; NOTCH1; and ADAMTS1;

    Sammanfattning : Glioblastoma is a most aggressive brain tumor with a median overall survival of less than two years. The current treatment is surgery, chemotherapy, and radiotherapy. However, glioblastoma is difficult to treat and recurs some time after treatment. LÄS MER

  3. 3. Intercellular protein transfer and regulation of inhibitory NK receptor accessibility

    Författare :Katja Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : NK cells are important players of innate immunity and capable of promoting specific responses of the adaptive immune system. NK cells possess the ability to recognise and eliminate virus-infected cells, tumour cells and allogeneic bone marrow grafts. LÄS MER

  4. 4. Astrocytic communication and cell death during metabolic depression and oxidative stress

    Författare :Christina Nodin; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :astrocyte; gap junction; ATP; ROS; oxidative stress; Annexin V; AIF; programmed cell death; Nrf2; scavenger; iodoacetate; SIN-1;

    Sammanfattning : Stroke is a major cause of death and adult disability in the western world. Most often, stroke is caused by the occlusion of a brain artery. Within the perfusion territory of the occluded vessel, various degrees of necrotic and delayed programmed cell death will occur if the occlusion persists, leading to expanding tissue damage. LÄS MER

  5. 5. Investigation of the intercellular transmission of α-synuclein, amyloid-β and TDP-43

    Författare :Christopher Sackmann; Martin Hallbeck; Emelie Severinsson; Poul Henning Jensen; Linköpings universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; α-synuclein; amyloid-β; TDP-43; cell to cell transmission;

    Sammanfattning : Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), frontotemporal lobar dementia (FTLD) and amyotrophic lateral sclerosis (ALS) are disorders characterized by the progressive deposition of proteinaceous inclusions throughout the brain in a predictable manner. Each disease is described by the involvement of different misfolded and aggregated proteins (AD, amyloid-β and tau; PD, α-synuclein; ALS and FTLD, TDP-43) that spread between anatomically connected brain regions, causing cell death in previously healthy regions. LÄS MER