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Visar resultat 1 - 5 av 187 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Probing Ligand Binding Mechanisms in Insulin-Regulated Aminopeptidases : Computational analysis and free energy calculations of binding modes

   Författare :Sudarsana Reddy Vanga; Hugo Gutiérrez-de-Terán; Johan Åqvist; Efstratios Stratikos; Uppsala universitet; []
   Nyckelord :Docking; Molecular Dynamics; Binding free energy; Linear Interaction Energy; Free Energy Perturbation; Insulin-Regulated Aminopeptidase; Angiotensin IV; Oxytocin; Vasopressin; HA08; Aryl sulfonamides; HFI compounds.;

   Sammanfattning : In recent years insulin-regulated aminopeptidase (IRAP) has emerged as a new therapeutic target for the treatment of Alzheimer’s disease and other memory-related disorders. So far, many potent and specific IRAP inhibitors had been disclosed, including peptides, peptidomimetics, and low-molecular-weight sulfonamides. LÄS MER

3. 2. Reality-based brain-computer interaction

   Författare :Daniel Sjölie; Lars-Erik Janlert; Johan Eriksson; John Waterworth; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; reality-based brain-computer interaction; virtual reality; reality-based interaction; brain-computer interface; activity theory; the free-energy principle; grounded cognition; Cognitive science; Kognitionsvetenskap; Computer science; Datalogi; människa-datorinteraktion; människa-datorinteraktion;

   Sammanfattning : Recent developments within human-computer interaction (HCI) and cognitive neuroscience have come together to motivate and enable a framework for HCI with a solid basis in brain function and human reality. Human cognition is increasingly considered to be critically related to the development of human capabilities in the everyday environment (reality). LÄS MER

4. 3. Exploring the Potential of Head Worn Displays for Manual Work Tasks in Industrial Environments

   Författare :Sebastian Felix Rauh; Cristian Bogdan; Gerrit Meixner; Mario Romero Vega; Alex Olwal; Mark Smith; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Head Worn Displays; Work Support; Augmented Reality; Computer Science; Datalogi; Human-computer Interaction; Människa-datorinteraktion;

   Sammanfattning : In this thesis I explore the potential of modern Head-Worn Displays for aiding manual work tasks in the manufacturing industries. In such settings, workers are already supported by using mobile hand-held devices that show instructions and enable the worker to document work tasks. LÄS MER

5. 4. Using Energy Fluxes to Analyze the Hydrodynamic Performance of Marine Propulsion Systems

   Författare :Jennie Andersson; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Propulsor-Hull interaction; Control volume analysis; RANS; Energy balance analysis; CFD;

   Sammanfattning : The strive towards more fuel efficient ships is a continuously ongoing process, motivated by both economic and regulatory reasons. An important aspects to consider for the final fuel consumption is the propulsion system performance in relevant operating conditions. LÄS MER

7. 5. Fluorine-Free Ionic Liquids and Electrolytes : From Synthesis to Energy Storage Applications

   Författare :Mukhtiar Ahmed; Faiz Ullah Shah; Patrik Johansson; Alexander Shaplov; Luleå tekniska universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ionic Liquids; Electrolytes; Sustainability; Lithium ion batteries; Flourine-Free; Chemistry of Interfaces; Gränsytors kemi;

   Sammanfattning : Since their introduction by Sony in 1990, lithium-ion batteries (LIBs) have acquired a sizable market share. They have the best energy densities, a high open circuit voltage, a low self-discharge rate, no memory effect, and a slow loss of charge when not in use. LÄS MER