Sökning: "integrons"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet integrons.

  1. 1. Co-operative recombination mechanisms promoting gene clustering and lateral transfer of antibacterial drug resistance

    Författare :Masood Kamali-Moghaddam; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Tn5090 Tn402; Mu-like transposons; serine recombinases; res site; integrons; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Pharmaceutical Microbiology; farmaceutisk mikrobiologi;

    Sammanfattning : Transposons of the Mu superfamily are widespread and have been shown to play an important role in the dissemination of antibiotic resistance among microorganisms. One of these elements, Tn5090/Tn402 is the basal vehicle of the type 1 integrons in which mobile resistance gene cassettes are inserted to form clusters and operons. LÄS MER

  3. 2. Modeling of bacterial DNA patterns important in horizontal gene transfer using stochastic grammars

    Författare :Mariana Buongermino Pereira; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Stochastic context-free grammars; hidden Markov model; conditional random fields; integrons; attC sites; secondary structure.; secondary structure.;

    Sammanfattning : DNA contains genes which carry the blueprints for all processes necessary to maintain life. In addition to genes, DNA also contains a wide range of functional patterns, which governs many of these processes. These functional patterns have typically a high variability, both within and between species, which makes them hard to detect. LÄS MER

  4. 3. Genital and urinary tract infections in pregnancy in southern India : diagnosis, management and impact om perinatal outcome

    Författare :Elizabeth Mathai; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Urinary tract infection; antimicrobial resistance; Chlamydia trachomatis; E Coli; CRP; neonatal infection; syphilis; nitrofurantoin; integrons; antenatal; India.;

    Sammanfattning : Background: Prevalence of sexually transmitted infections varies in different parts of the world. These infections, occurring during pregnancy, can result in adverse outcome. There is paucity of information on the prevalence, effects and management of such infections in pregnancy in India. LÄS MER

  5. 4. Deliberations on the impact of antibiotic contamination on dissemination of antibiotic resistance genes in aquatic environments

    Författare :Björn Berglund; Per-Eric Lindgren; Dan I. Andersson; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : The great success of antibiotics in treating bacterial infectious diseases has been hampered by the increasing prevalence of antibiotic resistant bacteria. Not only does antibiotic resistance threaten to increase the difficulty in treating bacterial infectious diseases, but it could also make medical procedures such as routine surgery and organ transplantations very dangerous to perform. LÄS MER

  7. 5. Molecular basis for trimethoprim and sulphonamide resistance in Gram negative pathogens

    Författare :Malin Grape; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Resistance to antibiotics is becoming an important global public health problem. Infectious diseases are still among the major causes of disease and death in many parts of the world and the possibilities to treat bacterial infections are now threatened due to the spread of antibiotic resistance. LÄS MER