Sökning: "intact core"

Visar resultat 1 - 5 av 37 avhandlingar innehållade orden intact core.

  1. 1. Computational modeling of mechanobiology in intact and healing rat Achilles tendon

    Författare :Thomas Notermans; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Collagen; Finite element model; Mechano-regulation; Mechanical Properties; Strain; Oxygen; Viscoelasticity;

    Sammanfattning : Tendons fulfill an important musculoskeletal function by enabling energy-efficient force transmission between muscles and bones. The tendon is a collagen-rich connective tissue that adapts to mechanical loading through mechanobiological processes. LÄS MER

  3. 2. Characterisation of the interaction between the Hepatitis B virus core antigen and B cells

    Författare :Una Lazdina; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HBcAg; B cells; B cell antigen receptor; co-stimulatory molecules; cytokines; T helper cells; cytotoxic T cells;

    Sammanfattning : The Hepatitis B virus (HBV) is a major cause of severe human liver disease globally. There are around 350 million persistent HBV carriers with a risk of development of liver disease including cirrhosis and hepatocellular carcinoma. LÄS MER

  4. 3. Structure, Bonding and Chemistry of Water and Hydroxyl on Transition Metal Surfaces

    Författare :Klas Andersson; Anders Nilsson; Falko Netzer; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; core-level spectroscopy; surface chemistry; water; hydroxyl; metal surfaces; adsorption; structure; hydrogen bonding; Chemical physics; Kemisk fysik;

    Sammanfattning : The structure, bonding and chemistry of water and hydroxyl on metal surfaces are presented. Synchrotron based x-ray photoelectron- and x-ray absorption spectroscopy along with density functional theory calculations mainly form the basis of the results. LÄS MER

  5. 4. The assembly of cytosolic lipid droplets and its effect on insulin sensitivity

    Författare :Pontus Boström; Göteborgs universitet; []
    Nyckelord :diabetes; lipid metabolism; insulin resistance; lipid droplets; ADFP; SNARE;

    Sammanfattning : Accumulation of neutral lipids, in particular triglycerides, in non-adipocytes is highly related to the development of insulin resistance and its consequences, type-2 diabetes and cardiovascular diseases. The accumulation of triglycerides occurs in so-called lipid droplets in the cytosol. LÄS MER

  7. 5. Hydrophobic interactions of serpins

    Författare :Sabina Janciauskiene; Enheten för kroniska inflammatoriska och degenerativa sjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteiner; enzymology; polymerization.; Proteins; conformational polymorphism; hydrophobic interaction; amyloid fibrils; Alzheimer`s peptide Ab; alpha-1-antichymotrypsin; C-terminal peptide; lithocholic acid; cholesterol; Key words: alpha-1-antitrypsin; bile acids; enzymologi;

    Sammanfattning : The proteins of the serpin family are primarily but not exclusively proteinase inhibitors, which share a common, similar structure. It is known that this structure undergoes major conformational changes upon cleavage in the serpin reactive site loop, and that these changes include rearrangements within the hydrophobic core of the molecule. LÄS MER