Sökning: "insulitis"
Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet insulitis.
1. Studies of the Pancreas: Implications for Type 1 Diabetes Aetiology
Sammanfattning : Type 1 diabetes (T1D) is a disease of severe insulin deficiency through loss of β cells in the endocrine pancreas. The T1D dogma maintains that a precipitating event unleashes autoimmunity in at-risk individuals, often measured through autoantibodies against β cell antigens. LÄS MER
2. Optical projection tomography based 3D-spatial and quantitative assessments of the diabetic pancreas
Sammanfattning : The gastrointestinal tract comprises a number of digestive organs including the stomach and pancreas. The stomach is involved in the digestion and short term storage of food while the pancreas is a mixed endocrine and exocrine gland which provides the body with hormones and enzymes essential for nutritional utilisation. LÄS MER
3. The Impact of Pancreatic Islet Vascular Heterogeneity on Beta Cell Function and Disease
Sammanfattning : Diabetes Mellitus is a group of complex and heterogeneous metabolic disorders characterized by hyperglycemia. Even though the condition has been extensively studied, its causes and complex pathologies are still not fully understood. The occurring damage to the pancreatic islets is strikingly heterogeneous. LÄS MER
4. Murine insulin-dependent diabetes mellitus : a model for disease development and protection
Sammanfattning : Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease caused by destruction of the insulin-producing beta cells in the pancreatic Langerhans' islets. This destruction is preceded by an infiltration of mononuclear leukocytes called insulitis. LÄS MER
5. Molecular and cellular mechanisms in the development of IDDM in non-obese diabetic mice
Sammanfattning : Insulin dependent diabetes mellitus (IDDM) is a disease caused by autoimmune destruction of the insulin producing b cells in the pancreas. The leukocytic infiltration into the b cell islets preceding disease is called insulitis. LÄS MER