Sökning: "insulin"

Visar resultat 11 - 15 av 1535 avhandlingar innehållade ordet insulin.

  1. 11. Insulin-Degrading Enzyme : A link between insulin resistance and Alzheimer's disease

    Författare :Helena Kullenberg; Marie Svedberg; Maria Kumlin; Thomas Nyström; Michael Alvarsson; Sophiahemmet Högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Background: Prior research has demonstrated an elevated risk of Alzheimer's disease (AD) among individuals diagnosed with type 2 diabetes mellitus (T2DM). Insulin resistance is a potential common link between these conditions, and it is associated with AD due to the insulin-degrading enzyme (IDE), which also degrades amyloid-β (Aβ) in the brain. LÄS MER

  3. 12. Assessment and Treatment of Impaired Insulin- Secretion and Action in Type 2 Diabetes

    Författare :Mozhgan Dorkhan; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes; insulin secretion; glucagon test; insulin resistance; insulin glargine; insulin tolerance test; thiazolidinediones; natriuretic peptides; adiponectin; thyroid associated ophthalmopathy; proinsulin;

    Sammanfattning : Type 2 diabetes (T2D) is a disease characterised by varying degrees of defect in insulin secretion and insulin sensitivity and associated with increased morbidity and mortality. Optimal glycaemic control reduces the progression of diabetic complications. LÄS MER

  4. 13. Dissertatio de micrometro objectivo quam ... publice ventilandam sistunt Dan Hallencreutz ... et Nicolaus Insulin Helsingus in audit. Carol. Maj. d. XIV Mart. ann. MDCCLXVII

    Författare :Daniel Hallencreutz; Niklas Insulin; Daniel Hallencreutz; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  5. 14. Insulin and IGF-I in type 1 diabetes

    Författare :Christina Hedman; Claes-Göran Östenson; Linköpings universitet; []
    Nyckelord :Type I diabetes; IGF-I; IGF system; insulin; insulin analogues; MEDICINE; MEDICIN;

    Sammanfattning : Patients with type I diabetes have alterations in the GH/IGF system with reduced levels of circulating IGF-I, as well as other disturbances in the components of the IGF system.Alterations of both local and circulating IGF-I and its binding proteins (IGFBPs) have been associated with metabolic and vascular manifestations of diabetes and also with atherosclerosis. LÄS MER

  7. 15. Membrane rafts and its GPI anchored complement inhibitors regulate insulin secretion

    Författare :Vini Nagaraj; Diabetes - öpatofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Membrane rafts; basal insulin secretion; regulated insulin secretion; CD59; CD55; SNARE proteins; insulin; pancreatic beta cells.;

    Sammanfattning : Type 2 diabetic patients usually exhibit an abnormal lipid profile. One such lipid that is constantly elevated in T2D is cholesterol. At the cellular level, cholesterol aids in tight packing of sphingolipids in certain regions of the plasma membrane and these specialized regions are termed ‘membrane rafts’, which act as signalling hubs. LÄS MER