Sökning: "insulin resistance"

Visar resultat 16 - 20 av 474 avhandlingar innehållade orden insulin resistance.

1. 16. Insulin resistance in pancreatic cancer

   Författare :Bengt Isaksson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Pancreatic cancer; glucose transport; glucose metabolism; insulin signaling; insulin resistance; uncoupling proteins; obstructive jaundice; IAPP; risk factors.;

   Sammanfattning : The dismal prognosis of pancreatic cancer (PC) is related to metabolic complications of the tumor. Impaired glucose tolerance or diabetes due to insulin resistance, and cachexia are observed early and frequently in these patients. The basic mechanisms of PC-associated insulin resistance and weight loss are not fully understood. LÄS MER

3. 17. Perioperative nutrition and insulin resistance

   Författare :Monika Svanfeldt; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Insulin sensitivity; insulin resistance; hyperinsulinaemic normoglycaemic clamps; wholebody glucose kinetics; whole-body protein kinetics; indirect calorimetry; surgery; carbohydrate loading; hypocaloric nutrition; bed rest and TPN;

   Sammanfattning : Surgical trauma induces a catabolic response with development of insulin resistance as a central and well-characterised feature. In insulin resistance, the stimulating effect of insulin on peripheral glucose uptake and the suppressing effect of insulin on endogenous glucose release are decreased, resulting in hyperglycaemia. LÄS MER

4. 18. Magnesium and the Insulin Resistance Syndrome

   Författare :Arvo Hänni; L Resnick; Uppsala universitet; []
   Nyckelord :Medical sciences; magnesium; calcium; insuline resistance syndrome; hypertension; lipids; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Geriatrics; geriatrik;

   Sammanfattning : Insulin resistance, defined as a state of reduced insulin-mediated glucose uptake in peripheral tissues, and disorders such as obesity, hypertension, and dyslipidemia, have been found to be associated in the conglomerate of the insulin resistance syndrome. Some antihypertensive drugs have been shown to decrease insulin sensitivity further. LÄS MER

5. 19. Insulin resistance and cardiovascular function - Observational, translational and interventional studies

   Författare :Helena Utkovic Westergren; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Insulin resistance; microvascular function; peripheral vascular function; coronary flow reserve; prognosis; myocardial perfusion scintigram; animal model;

   Sammanfattning : Background: Microvascular disease is now recognized as an important driver for cardiovascular mortality and morbidity. Diabetic patients are known to suffer from this condition, leading to e.g. coronary ischemia as well as kidney dysfunction. LÄS MER

7. 20. Polycystic ovary syndrome : A study on factors of potential impact on body fat and carbohydrate metabolism

   Författare :Gianluca Gennarelli; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; polycystic ovary syndrome; androgens; insulin; insulin resistance; body fat distribution; hypoglycaemia; adrenal; cortisol; ACTH; leptin; gestational diabetes mellitus; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; Obstetrics and Gynaecology; obstetrik och gynekologi;

   Sammanfattning : The aim of the present thesis was to investigate some factors underlying the metabolic, anthropometric, and endocrine abnormalities of women with the polycystic ovary syndrome (PCOS).An iv insulin tolerance test (0.15 IU bolus) showed substantially preserved glucose counterregulation in women with PCOS (n=18). LÄS MER