Sökning: "insulin glargine"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden insulin glargine.

  1. 1. Assessment and Treatment of Impaired Insulin- Secretion and Action in Type 2 Diabetes

    Författare :Mozhgan Dorkhan; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes; insulin secretion; glucagon test; insulin resistance; insulin glargine; insulin tolerance test; thiazolidinediones; natriuretic peptides; adiponectin; thyroid associated ophthalmopathy; proinsulin;

    Sammanfattning : Type 2 diabetes (T2D) is a disease characterised by varying degrees of defect in insulin secretion and insulin sensitivity and associated with increased morbidity and mortality. Optimal glycaemic control reduces the progression of diabetic complications. LÄS MER

  2. 2. Glycaemic control: evaluation of HbA1c as a risk factor and the effect of modern insulins in clinical practice

    Författare :Marcus Lind; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :HbA1c; glargine; lispro; time; retinopathy; clinical practice; electronical tracking; record system;

    Sammanfattning : One of the ultimate goals of diabetes care is to minimise diabetic complications. When evaluating insulins it is important to understand what extent of improvements in glycaemic control is clinically relevant in preventing diabetic complications. LÄS MER

  3. 3. Insulin-like growth factor -I deficiency, insulin sensitivity, and glucose metabolism

    Författare :Klas Ekström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : In children and adolescents, growth hormone (GH) and insulin-like growth factor-I (IGF-I) act in concert to stimulate linear growth; however, the effects on glucose metabolism are in opposition. GH increases insulin resistance by lipolysis. LÄS MER

  4. 4. IGF-I receptors, insulin receptors and insulin/IGF-I hybrid receptors in human endothelial cells : with special reference to diabetes

    Författare :Marloes Dekker Nitert; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Patients with diabetes mellitus are known to develop vascular complications, which occur as macroangiopathy, atherosclerosis and mediasclerosis, as well as microangiopathy, e.g. retinopathy and nephropathy. The precise mechanisms causing these complications have not yet been elucidated. LÄS MER

  5. 5. Long-acting insulin analogs in type 1 diabetes : effects on metabolic control, endogenous insulin production and the GH-IGF-axis

    Författare :Jenny Salemyr; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : The treatment goal in type 1 diabetes is to achieve near-normal glycemia. Despite of the advancements of subcutaneous insulin therapy and glucose monitoring, metabolic control is not fully normalized and secondary endocrine disturbances in the growth-hormone (GH) - Insulin-like Growth Factor (IGF)-axis are important for the deterioration of metabolic control, particularly in children at puberty. LÄS MER