Sökning: "insulator"

Visar resultat 1 - 5 av 225 avhandlingar innehållade ordet insulator.

  1. 1. CTCF and Epigenetic Regulation of the H19/Igf2 Locus

    Författare :Vinod Pant; Rolf Ohlsson; Rainer Reinkawitz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Imprinting; Chromatin; H19; Igf2; CTCF; Insulator; methylation; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : An overall coordination between the expressions of genes is required for the proper development of an individual. Although most genes are expressed from both the constituent alleles of the genome, a small subset of autosomal genes are preferentially expressed from only one of the parental alleles, a phenomenon known as genomic imprinting. LÄS MER

  3. 2. Epigenetic Regulation and Reprogramming of the H19 Imprinting Control Region

    Författare :Piero Mariano; Rolf Ohlsson; Karl Ekwall; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Imprinting; chromatin; H19; Igf2; CTCF; Insulator; methylation; Boris; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : The development of a new individual from the fertilized oocyte can ultimately be seen as the consequence of the establishment and maintenance of specific patterns of gene expression. Although regulation of gene activity occurs at different levels, cellular specialization and differentiation are the results of developmental cues that essentially take place at the transcriptional level. LÄS MER

  4. 3. Estimation of hydrophobicity of insulating surfaces by studying sessile water drops

    Författare :Marcus Berg; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Materials science; hydrophobicity; contact angle; insulator; water; silicone; image processing; image analysis; Young-Laplace equation; droplet; axisymmetric; Materialvetenskap; Materials science; Teknisk materialvetenskap; Electricity; Esp The Study Of Transients and Discharges; elektricitetslära; ssk studiet av transienter och urladdning;

    Sammanfattning : Today, the traditional insulator materials for high voltage powerlines, i.e. glass and porcelain, are gradually being replaced with new materials, most notably silicone rubber. LÄS MER

  5. 4. Epigenetic Regulation of Replication Timing and Signal Transduction

    Författare :Rosita Bergström; Aristidis Moustakas; Carl-Henrik Heldin; Rolf Ohlsson; Alain Mauviel; Uppsala universitet; []
    Nyckelord :Cell and molecular biology; Chromatin; CTCF; Epigenetics; Genomic Imprinting; H19; Id; Igf2; Insulator; Replication; Signal Transduction; Smad; TGF-β; Transcription; Cell- och molekylärbiologi;

    Sammanfattning : Upon fertilization the paternal and maternal genomes unite, giving rise to the embryo, with its unique genetic code. All cells in the human body are derived from the fertilized ovum: hence they all contain (with a few exceptions) the same genetic composition. LÄS MER

  7. 5. The Functional Significance and Chromatin Organisation of the Imprinting Control Regions of the H19 and Kcnq1 Genes

    Författare :Meena Kanduri; Rolf Ohlsson; Karl Ekwall; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; DNA methylation; Imprinting control region; Chromatin; Insulator; Nucleosome positioning; Genetik; Genetics; Genetik;

    Sammanfattning : Genomic imprinting is a phenomenon through which a subset of genes are epigenetically marked during gemtogenisis. This mark is maintained in the soma to often manifest parent of origin-specific monoalleleic expresson patterns. LÄS MER