Sökning: "instrumental genes"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden instrumental genes.

1. 1. Orphan Genes Bioinformatics : Identification and properties of de novo created genes

   Författare :Walter Basile; Arne Elofsson; Diethard Tautz; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; de novo; orphans; evolutionary genetics; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Sammanfattning : Even today, many genes are without any known homolog. These "orphans" are found in all species, from Viruses to Prokaryotes and Eukaryotes. For a portion of these genes, we might simply not have enough data to find homologs yet. LÄS MER

3. 2. Designing for the incorporation of programming in mathematical education : Programming as an instrument for mathematical problem solving

   Författare :Andreas Borg; Kenneth Ruthven; Maria Fahlgren; Chantal Buteau; Karlstads universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Mathematics; math; upper secondary; problem solving; programming; coding; instrument; instrumental genesis; education; mathematics education; scheme; matematik; skola; utbildning; problemlösning; programmering; kodning; instrument; instrumental genes; utbildning; matematikdidaktik; schema; Pedagogiskt arbete; Educational Work; Matematikdidaktik; Mathematics didactics;

   Sammanfattning : This study explored Swedish upper secondary school students’ use of programming for mathematical purposes. The aim of the study was to investigate the process through which students learn how to use a programming environment as a technical artefact during mathematical problem solving and how the orchestration of such learning situations could facilitate this process. LÄS MER

4. 3. Modern Genes : Body, Rationality and Ambivalence

   Författare :Niclas Hagen; Avdelningen för etnologi; []
   Nyckelord :HUMANIORA; HUMANITIES; Everyday experiences; Modernity; Everyday Life; Lifeworld; System; Genetics; Huntington’s disease.;

   Sammanfattning : The main objective of this ethnological thesis is to investigate the linkage between everyday life with a genetic disease and intrinsic patterns of modernity. The thesis is a compilation thesis that contains four individual articles each addressing the everyday experience of a genetic disease from different angles, with different research questions and theoretical presumptions. LÄS MER

5. 4. Comparative sequencing of candidate genes in complex disease

   Författare :Shane McCarthy; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :DNA; Sequencing; Complex Disease; Candidate Gene;

   Sammanfattning : Complex multi-factorial diseases such as cardiovascular, metabolic, neurological and respiratory disorders affect a great number of people across the world. In the post-Human Genome Sequencing era, genome wide association studies are increasingly viable alternatives to linkage approaches in locating disease genes. LÄS MER

7. 5. Functional association networks for disease gene prediction

   Författare :Dimitri Guala; Erik L L Sonnhammer; Hjalmar Brismar; Yves Moreau; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; network biology; biological networks; network prediction; functional association; functional coupling; network integration; functional association networks; genome-wide association networks; gene networks; protein networks; fret; functional enrichment analysis; network cross-talk; pathway annotation; gene prioritisation; network-based gene prioritization; benchmarking; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Sammanfattning : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. LÄS MER