Sökning: "insertional sequence."
Hittade 4 avhandlingar innehållade orden insertional sequence..
1. Molecular analysis of Streptococcus pyogenes and its interactions with the human host
Sammanfattning : Streptococcus pyogenes causes infections only in humans, from trivial tonsillitis to life-threatening conditions. One of its most important virulence factors is the M-like protein family conferring resistance to phagocytosis to the bacterium. The M-like proteins are surface exposed rod-like molecules attached to the cell wall. Each strain of S. LÄS MER
2. Marginally hydrophobic transmembrane α-helices shaping membrane protein folding
Sammanfattning : Most membrane proteins are inserted into the membrane co-translationally utilizing the translocon, which allows a sufficiently long and hydrophobic stretch of amino acids to partition into the membrane. However, X-ray structures of membrane proteins have revealed that some transmembrane helices (TMHs) are surprisingly hydrophilic. LÄS MER
3. A genetic approach to the identification of new components regulating development in Arabidopsis thaliana
Sammanfattning : Two new genes involved in important processes of plant development were identified in the model plant Arabidopsis thaliana. The genes were isolated from mutants generated through insertional mutagenesis based on a transposon tagging approach. LÄS MER
4. Roles of p16INk a and PDGF-B in glioma
Sammanfattning : Gliomas are diffuse astrocytic tumors of the central nervous system (CNS) which usually affect adults. This thesis work has focused on molecular mechanisms of altered growth control in glioma, and the significance of two gene products belonging to pathways commonly affected in glioma, p16INK4a and PDGF-B, has been investigated in vitro and in vivo. LÄS MER