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Visar resultat 1 - 5 av 329 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Immunity & the butterfly : A functional genomic study of natural variation in immunity

    Författare :Naomi L.P. Keehnen; Christopher W. Wheat; Brian Lazzaro; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; eco-immunology; functional genomics; transcriptomics; innate immunity; selection dynamics; melanization; phagocytosis; population genetics; Pieris napi; populationsgenetik; Population Genetics;

    Sammanfattning : Butterflies are ubiquitous and abundant, occurring in a wide variety of environments that contain diverse microbial communities with varied pathogenic pressures. These pathogens and parasites present a constant threat to organisms, and have led to the evolution of complex and intricate immune responses. LÄS MER

  2. 2. Studies of Innate and Adaptive Immunity in Islet Transplantation

    Författare :Maria Hårdstedt; Olle Korsgren; Bo Nilsson; Thierry Berney; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetes; islet transplantation; islets of Langerhans; xenotransplantation; nonhuman primate; blood; whole blood model; innate immunity; adaptive immunity; IBMIR; chemokines;

    Sammanfattning : Clinical islet transplantation is today an established alternative treatment for a selected group of type 1 diabetes patients. The predominant technique for transplantation is infusion of islets in the liver via the portal vein. LÄS MER

  3. 3. Peptidoglycan Recognition Proteins : Major Regulators of Drosophila Immunity

    Författare :Peter Mellroth; Håkan Steiner; Julien Royet; Stockholms universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Innate immunity; peptidoglycan recognition protein; PGRP; Toll; Imd; Drosophila immunity; Microbiology and immunology; Mikrobiologi och immunologi;

    Sammanfattning : All eukaryotic organisms have an innate immune system characterized by germ-line encoded receptors and effector molecules, which mediate detection and clearance of microbes such as bacteria, fungi, and parasites. VertebrateDrosophila as a genetically tractable organism with a This thesis concerns the peptidoglycan recognition protein (PGRP) gene family in the fruit fly. LÄS MER

  4. 4. Vascular Interactions in Innate Immunity and Immunothrombosis: : Models of Endothelial Protection

    Författare :Sofia Nordling; Peetra Magnusson; Paul Kubes; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endothelial cells; Thrombosis; Innate immunity; Immunothrombosis; Thromboinflammation; Immunologi; Immunology;

    Sammanfattning : The phenomenon known as immunothrombosis has garnered increased attention over the last few years. Much work has been done to characterize the cross talk between hemostasis and the innate immune system. LÄS MER

  5. 5. Innate immunity in human atherosclerosis and myocardial infarction : Role of CARD8 and NLRP3

    Författare :Geena Paramel Varghese; Karin Fransén; Allan Sirsjö; Liza Ljungberg; Johan Frostegård; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; Inflammasome; NLRP3; CARD8; Myocardial infarction; Endothelial cells; Polymorphism; IL-1β; Cytokines; Innate immunity; Biomedicin; Biomedicine;

    Sammanfattning : Atherosclerosis is complex inflammatory disease of the arterial wall with progressive accumulation of lipids and narrowing of the vessel. Increasing evidence suggest that inflammation plays an important role in plaque stability and often accelerate cardiovascular events such as myocardial infarction (MI). LÄS MER