Sökning: "innate immune cells"
Visar resultat 1 - 5 av 467 avhandlingar innehållade orden innate immune cells.
1. Effects of Complement Opsonization of HIV on Dendritic Cells : and Implications for the Immune Response
Sammanfattning : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. LÄS MER
2. Functions and memory features of adaptive- and innate immune cells in physiological and inflammatory settings
Sammanfattning : The immune system is a complex but well-regulated network which cooperates with the microbiota to maintain optimal homeostasis under physiological settings. A number of factors display the capacity to alter the immune system and thus microbiota crosstalk including host genetics, diet, environmental influences and drugs such as antibiotics or chemotherapeutic agents. LÄS MER
3. Plasmodium falciparum-mediated modulation of innate immune cells: responses and regulation
Sammanfattning : Plasmodium falciparum (P. falciparum) infection modulates the response of innate immune cells. The aim of this work was to study the impact of P. falciparum infection and P. LÄS MER
4. Dendritic cells in cancer immunotherapy
Sammanfattning : Dendritic cells (DCs) play a central role in the initiation and regulation of innate and adaptive immune responses and have increasingly been applied as vaccines for cancer patients. Ex vivo generation and antigen loading of monocyte-derived DCs allows a controlled maturation, with the aim of imprinting different DC functions that are essential for their subsequent induction of a T cell-mediated anti-tumor response. LÄS MER
5. Regulatory aspects of innate immune responses
Sammanfattning : Activation of innate immunity is regulated by a variety of signaling molecules within the immune cells. The present thesis was aimed to improve our understanding of innate signaling mechanism and their possible use as bio-indicators of exposure and disease. LÄS MER