Sökning: "innate immune activation"
Visar resultat 1 - 5 av 279 avhandlingar innehållade orden innate immune activation.
1. Effects of Complement Opsonization of HIV on Dendritic Cells : and Implications for the Immune Response
Sammanfattning : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. LÄS MER
2. Regulatory aspects of innate immune responses
Sammanfattning : Activation of innate immunity is regulated by a variety of signaling molecules within the immune cells. The present thesis was aimed to improve our understanding of innate signaling mechanism and their possible use as bio-indicators of exposure and disease. LÄS MER
3. Innate immune mechanisms of atherosclerosis
Sammanfattning : Atherosclerosis is a multi-factorial immune mediated disease in arterial wall characterized by lipid driven inflammation through activation of the immune system. Chronic vascular inflammation is an important component that modulates atherosclerosis evolution and its complications. LÄS MER
4. Innate immune cell response in sepsis
Sammanfattning : Leukocyte recruitment is known to be a key feature at sites of inflammation and important in the combat against infectious agents. However, the mechanisms of leukocyte recruitment in the pulmonary microvasculature in response to local and systemic inflammation remain elusive. LÄS MER
5. Plasmodium falciparum-mediated modulation of innate immune cells: responses and regulation
Sammanfattning : Plasmodium falciparum (P. falciparum) infection modulates the response of innate immune cells. The aim of this work was to study the impact of P. falciparum infection and P. LÄS MER