Sökning: "injectable"

Visar resultat 11 - 15 av 36 avhandlingar innehållade ordet injectable.

  1. 11. Valorization of Kraft Lignin by Fractionation and Chemical Modifications for Different Applications

    Författare :Selda Aminzadeh; Mikael Lindström; Hasan Jameel; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Lignin Valorization- LignoBoost Lignin-Clean Flow Black Lignin- Characterization-Chemical modifications-Fractionation-applications; Chemical Engineering; Kemiteknik;

    Sammanfattning : AbstractLignin is one of the most abundant biopolymers. Approximately 70 million tons of technical lignin is generated annually, but only little is used for products other than energy. The complexity of lignin hinders full utilization in high-value products and materials. LÄS MER

  3. 12. Design of solid dosage forms for mucosal vaccination - Investigations on the influence of excipients on product performance

    Författare :Annika Borde; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; hydrophilic matrix tablets; osmotic pressure; protein release; freeze-drying; Vibrio cholerae; mucoadhesion; Bradford Assay; sublingual vaccine tablet; mucosal vaccination;

    Sammanfattning : Most vaccines today are liquid formulations for parental administration. However, there are several drawbacks connected to these vaccines. Since injectable vaccines only induce systemic antibody responses, they are not effective against the various pathogens that affect mucosal surfaces with poor permeability for serum-derived antibodies, e.g. LÄS MER

  4. 13. Broadly protective nanoparticle-based mucosal vaccine against influenza virus infection

    Författare :Valentina Bernasconi; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucosal vaccination; Influenza A virus; CTA1-DD; Nanoparticle; Targeted adjuvant; Nasal immunization; Oral immunization; Neonatal vaccine; Universal vaccine;

    Sammanfattning : Influenza is one of the major viral diseases affecting humans and it is responsible for three to five million cases of severe illness and about 250.000 to 500.000 deaths each year worldwide. LÄS MER

  5. 14. Extracellular matrix mimetic multi-functional scaffolds for tissue engineering and biomedical applications

    Författare :Ranjithkumar Ravichandran; Jaywant Phopase; Anthony Turner; Ann-Christine Albertsson; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Regeneration of functional tissues or complex organs via the combination of viable cells, biomimetic scaffolds, morphogenic factors, and external biophysical cues are the principle aims of Tissue Engineering (TE). TE relies on the use of artificial 3D scaffolds that can mimic the microenvironment of native tissue to harness the regenerative potential of cells. LÄS MER

  7. 15. Environment-Sensitive Multifunctional Drug Delivery Systems

    Författare :Jian Qin; Mamoun Muhammed; Marcus Textor; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Materials chemistry; Materialkemi;

    Sammanfattning : Drug delivery systems (DDS) with multiple functionalities such as environment-sensitive drug release mechanisms and visualization agents have motivated the biomedical community as well as materials chemists for more than a decade. This dissertation is concerned with the development of nanoparticles for multifunctional DDS  to tackle several crucial challenges in these complex systems, including polymeric nanospheres which respond to temperature change, superparamagnetic iron oxide nanoparticles/polymeric composite for magnetic resonance imaging contrast agents and drug carriers, immunoresponse of nanomaterials and injectable magnetic field sensitive ferrogels. LÄS MER