Sökning: "inhibitory receptors"
Visar resultat 1 - 5 av 280 avhandlingar innehållade orden inhibitory receptors.
1. Signaling via Orexin Receptors : A Pharmacological Study
Sammanfattning : The orexin receptors are a pair of newly discovered G-protein coupled receptors which are activated by the neuropeptides orexins and play a role in sleep/vigilance, apetite/metabolism and neuroendocrine regulation. On a cellular level receptor activation results in, to name but a few effects, elevation of intracellular calcium and depolarisation. LÄS MER
2. Fc receptors and feedback regulation by antibodies
Sammanfattning : The purpose of this investigation was to determine the role of Fc receptors for IgG (FcγRI, FcγRIIB, FcγRIII and FcRn) in immunoregulation. IgG is known to enhance the response to soluble antigens such as bovine serum albumin whereas the response to particulate antigens is suppressed. LÄS MER
3. Cellular receptors for viruses with ocular tropism
Sammanfattning : Several viruses from different virus families are known to cause ocular infections, e.g. members of the Adenoviridae, Picornaviridae and the Herpesviridae families. These infections are spread by contact and in the case of adenoviruses (Ads) and picornaviruses they are also highly contagious. LÄS MER
4. Striatal adenosine A2A receptors
Sammanfattning : The nucleoside adenosine exerts a modulatory action in the central nervous system by activating G-protein coupled receptors. Four such receptors are cloned and pharmacologically characterized: A1, A2A, A2B and A3. Caffeine, the most widely consumed psychostimulant, acts as an adenosine receptor antagonist predominantly on the first two. LÄS MER
5. Inhibitory receptors of natural killer cells : specificity and regulation
Sammanfattning : Immunological surveillance of organs and tissues for pathogens and transformed cells by immune cells and their soluble mediators is of outmost importance for the well-being of the host. The natural killer (NK) cell is an example of such an immune cell. LÄS MER