Sökning: "inhibitory activity"
Visar resultat 6 - 10 av 449 avhandlingar innehållade orden inhibitory activity.
6. Ethanol-induced modulation of dopamine transmission and synaptic activity in striatal subregions - focus on inhibitory receptors
Sammanfattning : Background: Alcoholism is a chronic brain disease, affecting neurocircuitries involved in reward and learning. The rewarding effects of alcohol (ethanol) are believed to result from increased dopamine levels in the nucleus accumbens (nAc) via the mesolimbic system. LÄS MER
7. Physiological and pathophysiological regulation of ECL-cell activity
Sammanfattning : The ECL cells are endocrine/paracrine cells located in the acid-producing part of the stomach. They produce and secrete histamine and chromogranin A-derived peptides in response to circulating gastrin. Mobilized histamine stimulates acid secretion from adjascent parietal cells. LÄS MER
8. Heart Rate Variability in Stress-related Fatigue, Adolescent Anxiety and Depression and its Connection to Lifestyle
Sammanfattning : Heart rate varies constantly as a consequence of activity in the sympathetic and parasympathetic autonomic nervous systems (SNS and PNS). In short-term recordings, heart rate variability (HRV) is mostly related to the inhibitory activity of the vagal nerves, which are part of the PNS. LÄS MER
9. Growth control mechanisms in normal and neoplastic mammalian cells
Sammanfattning : The main theme of the studies presented in this thesis is, the growth control mechanisms whose loss in normal cells predispose to or cause cancer. The balance between growth inhibitory and stimulatory mechanisms is crucial for the development and maintenance of a normal animal. LÄS MER
10. Structure-activity and resistance studies of HIV-1 protease inhibitors
Sammanfattning : The present investigation was undertaken in order to identify inhibitors of HIV-1 protease that would be efficient in vivo and against HIV-1 protease carrying mutations known to confer resistance to inhibitors in clinical use. A second interest was to understand details of inhibitory mechanisms and to gain understanding of the molecular details of resistance. LÄS MER