Sökning: "inhibitory activity"

Visar resultat 21 - 25 av 449 avhandlingar innehållade orden inhibitory activity.

  1. 21. Regulation of calcium flux by activating and inhibitory receptor crosstalk in NK cells

    Författare :Sridharan Ganesan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The birth of a new born child kicks off the immune system to be on call and to respond promptly to threats from the environment. Natural Killer cells, classified as a member of the innate lymphoid cell family, express various activating, inhibitory, adhesion and cytokine receptors as well as MHC class I molecules on their surfaces, by which they interact with surrounding cells and perform various immunological function. LÄS MER

  2. 22. Modulation of invariant NKT cell activity by cytokines and receptors in human disease

    Författare :Carlotta Kuylenstierna; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Invariant natural killer T (NKT) cells are innate-like lymphocytes with both immunoregulatory and cytotoxic functions that play a role as activators and regulators of the immune response in many diseases. NKT cells are believed to bridge the innate and adaptive immune systems by rapidly producing large quantities of cytokines after recognition of CD1d-presented lipid antigens. LÄS MER

  3. 23. In vivo and in vitro models for determination of antiviral activity and resistance

    Författare :Ewa Ljungdahl Ståhle; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The AIDS epidemic has been the driving force for the discovery of substances that inhibit the replication of human immunodeficiency virus (HIV). Much interest has earlier focused on a single gene product central to the life cycle of HIV and to all other retroviruses: the reverse transcriptase (RT), the enzyme responsible for synthesis of DNA from viral RNA. LÄS MER

  4. 24. On the role of parvalbumin interneurons in neuronal network activity in the prefrontal cortex

    Författare :Nicolas Gustavo Guyon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The prefrontal cortex (PFC) is an area important for executive functions, the initiation and temporal organization of goal-directed behavior, as well as social behaviors. Inhibitory interneurons expressing parvalbumin (PV) have a vital role in modulating PFC circuit plasticity and output, as inhibition by PV interneurons on excitatory pyramidal neurons regulates the excitability of the network. LÄS MER

  5. 25. Biorefining of lignocellulose : Detoxification of inhibitory hydrolysates and potential utilization of residual streams for production of enzymes

    Författare :Adnan Cavka; Leif J. Jönsson; John N. Saddler; Umeå universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Lignocellulosic biomass is a renewable resource that can be utilized for the production of biofuels, chemicals, and bio-based materials. Biochemical conversion of lignocellulose to advanced biofuels, such as cellulosic ethanol, is generally performed through microbial fermentation of sugars generated by thermochemical pretreatment of the biomass followed by an enzymatic hydrolysis of the cellulose. LÄS MER