Sökning: "inhaled particles"
Visar resultat 1 - 5 av 30 avhandlingar innehållade orden inhaled particles.
1. Fine and Ultrafine Particles from Combustion Sources - Investigations with In-situ Techniques
Sammanfattning : Fine airborne particles are associated with adverse health effects in the human population. The aim of this research was to develop and evaluate methods for in-situ characterisation of fine and ultrafine particles and to determine their deposition in the human airways. LÄS MER
2. Applications of Magnetic Tracers in the Human Lung and Gastrointestinal Tract
Sammanfattning : The use of ferrimagnetic material as a tracer represents a noninvasive approach in physiological measurements. Concerning the lung, magnetopneumography, MPG, is a unique technique to estimate retained dust in the lung, using the magnetizable dust fraction as a tracer. First a strong constant magnetic field is briefly applied to the thorax. LÄS MER
3. Experimental Determination of the Deposition of Aerosol Particles in the Human Respiratory Tract
Sammanfattning : BACKGROUND: Aerosol particles have, since the antiquity, been linked to adverse effects on human health. It is estimated that the particles in urban air pollution cause at least 100,000 deaths in Europe each year, whereof 5,000 in Sweden. LÄS MER
4. Deposition and absorption of inhaled drugs
Sammanfattning : Main objectives of this thesis were to evaluate a gamma scintigraphic method used to quantify drug aerosol deposition in the lung, to investigate the influence of two aerosol inhalation parameters on the distribution of inhaled dry powder within the airways, to assess pulmonary absorption kinetics and bioavailability of an inhaled hydrophilic solute in relation to site of deposition, and to assess the influence of a surface active agent (sodium taurocholate, a bile salt) on the deposition and absorption of an inhaled hydrophilic solute. Repeated planar gamma scintigraphy was found to provide the same information on total pulmonary drug deposition as an independent method that involved assessments of urinary drug recovery after blockage of gastrointestinal drug absorption when all of the critical parts of the methodological procedures were accurately and meticulously executed. LÄS MER
5. Deposition and clearance of inhaled particles in patients with obstructive airway diseases
Sammanfattning : A large part of the population (at least 10%) suffers from asthma or chronic bronchitis. Knowledge of deposition and clearance of inhaled particles in the respiratory tract in this group of patients is essential for estimating environmental health hazards, as well as optimal effects of therapeutic aerosols. LÄS MER