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Visar resultat 1 - 5 av 569 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Endogenous proteins as markers of glomerular function and dysfunction

    Författare :Jan Tencer; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glomerular filter; amyloidosis; glomerulonephritis; glomerular disease; proteins; proteinuria; Urology; nephrology; Urologi; nefrologi;

    Sammanfattning : Plasma and urine concentrations of endogenous proteins are frequently used in the diagnosis of kidney diseases and in studies of glomerular filter function. The main issues addressed in these studies were: storage of urine samples for subsequent protein analysis, use of protein concentrations in urine and in plasma in health and as markers of glomerular diseases, and the application of renal plasma-to-urine clearance of endogenous proteins in estimating the size-selectivity properties of the glomerular capillary wall. LÄS MER

  2. 2. Structural studies of proteins in apoptosis and lipid signaling

    Författare :Maria Dolores Herman Moreno; Pär Nordlund; Markus Gruetter; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; proteins; crystal structure; apoptosis; cancer; CoFi-Blot; kinases; lipid signaling; Structural biology; Strukturbiologi; Structural Biology; strukturbiologi;

    Sammanfattning : Signaling pathways control the fate of the cell. For example, they promote cell survival or commit the cell to death (apoptosis) in response to cell injury or developmental stimuli, decisions, which are vital for the proper development and functioning of metazoan. LÄS MER

  3. 3. The impact of Staphylococcus aureus surface proteins on virulence

    Författare :Niklas Palmqvist; Göteborgs universitet; []
    Nyckelord :Staphylococcus aureus; septic arthritis; sepsis; virulence; cell wall-anchored proteins; surface proteins; fibrinogen.;

    Sammanfattning : Staphylococcus aureus is an important pathogen in humans with the potential to cause life-threatening invasive infections, including sepsis and septic arthritis. The pathogenicity of S. aureus depends on the expression of a variety of virulence factors. LÄS MER

  4. 4. Inflammatory proteins in the CNS-relation to Alzheimer's disease

    Författare :Catharina Lindberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Most neurodegenerative disorders are characterised by an inflammatory process in the brain. Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common form of dementia in the elderly. Activated astrocytes and microglia surrounding the amyloid plaques represent evidence for neuroinflammation in the AD brain. LÄS MER

  5. 5. Granulocyte Adhesion to Matrix Proteins and the Effect on the Release of Granule Proteins : Development of a Simple Method and its Application in Experimental and Clinical Studies

    Författare :Xiaoyan Xu; Joachim Lundahl; Uppsala universitet; []
    Nyckelord :Medical sciences; Eosinophils; Neutrophils; Adhesion; Release of ECP; Extracellular matrix proteins; Granulocytes; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

    Sammanfattning : Granulocyte adhesion and release of their granule proteins are key steps during selective accumulation of a certain cell to an inflammatory site. Eosinophils are specifically recruited to sites of allergic inflammation and parasitic infection, whereas neutrophil influx predominates in bacterial infection and rheumatoid arthritis. LÄS MER