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Visar resultat 1 - 5 av 228 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Chlamydia pneumoniae in Aortic Valve Sclerosis and Thoracic Aortic Disease : Aspects of Pathogenesis and Therapy

   Författare :Christina Nyström-Rosander; Kenneth Persson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; Chlamydia pneumoniae; aortic valve sclerosis; trace elements; thoracic aorta; antibiotics; Polymerase Chain Reaction PCR ; electron microscopy EM ; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar; infektionssjukdomar; Infectious Diseases;

   Sammanfattning : The obligate intracellular bacterium Chlamydia pneumoniae (Cp), a common human pathogen, has been associated with atherosclerotic cardiovascular disease. The aetiology of non-rheumatic aortic valve sclerosis has, however, not been clarified. LÄS MER

3. 2. Genetic genealogy and epidemiology of Francisella

   Författare :Kerstin Svensson; Anders Johansson; Mats Forsman; Sam R. Telford III; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; tularemia; genotyping; epidemiology; GIS; Infectious diseases; Infektionssjukdomar; Infectious Diseases; infektionssjukdomar;

   Sammanfattning : This thesis is about analyzing genetic differences among isolates of Francisella tularensis – the tularemia-causing bacterium. To elucidate how these bacterial isolates are related, and their geographical and genetic origins, I have developed typing assays for Francisella and used them to study the epidemiology of tularemia. LÄS MER

4. 3. Travel – a risk factor for disease and spread of antibiotic resistance

   Författare :Martin Angelin; Helena Palmgren; Birgitta Evengård; Anders Johansson; Anu Kantele; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Accident Prevention; Alcohol Drinking; Anti-Bacterial Agents; Antimalarials; Beta-Lactamases; Drug-Resistance; Bacterial; Enterobacteriaceae; Health Knowledge; Attitudes; Practice; High-Throughput Nucleotide Sequencing; Medication Adherence; Metagenome; Metagenomics; Patient Compliance; Proteobacteria; Risk Reduction Behaviour; Risk-Taking; Safe Sex; Travel medicine; Travel; Vaccination; Infectious Diseases; infektionssjukdomar; mikrobiologi; Microbiology;

   Sammanfattning : As international travel is rapidly increasing, more people are being exposed to potentially more antibiotic resistant bacteria, a changed infectious disease epidemiology, and an increased risk of accidents and crime. Research-based advice is needed to adequately inform travellers about these risks. LÄS MER

5. 4. Sex differences in immune response and sex hormone receptor expression in healthy individuals and during viral infection

   Författare :Peik M. A. Brundin; Anders F. Johansson; Ivan Nalvarte; Carl-Johan Treutiger; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; immune response; menstrual cycle; puumala virus; hantavirus; torque teno virus; sex hormones; sex hormone receptors; estrogen receptors; estrogen receptor beta2; sex differences; microbiome; virome; endocrinology; peripheral blood mononuclear cells; qPCR; Infectious Diseases; infektionssjukdomar; medicinsk virologi; Medical Virology; immunologi; Immunology; Medical Cell Biology; medicinsk cellbiologi; molekylärbiologi; Molecular Biology; Medicine; medicin; obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : There is sex-bias in morbidity and mortality from infectious diseases. Infections kill more men than women and several studies have pointed out differences in the immune system as a reason. The sex hormones estrogen, progesterone and testosterone all shape the effect of the immune response on multiple levels. LÄS MER

7. 5. Modulating Organ Dysfunction in Experimental Septic Shock : Effects of Aminoglycosides, Antiendotoxin Measures and Endotoxin Tolerance

   Författare :Markus Castegren; Jan Sjölin; Claes Frostell; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipopolysaccharide; animal model; pig; tobramycin; endotoxin elimination; immunoparalysis; secondary sepsis; Infectious diseases; Infektionssjukdomar; Infektionssjukdomar; Infectious Diseases;

   Sammanfattning : Sepsis is a common diagnose in the intensive care population, burdened with a high mortality. The systemic inflammatory reaction underlying the development of septic organ dysfunction can be modeled using Gram-negative bacterial lipopolysaccharide, endotoxin. LÄS MER