Sökning: "infectious diseases Microbiology Bacteriology"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden infectious diseases Microbiology Bacteriology.

  1. 1. Molecular epidemiology of coagulase-negative staphylococci in hospitals and in the community

    Författare :Micael Widerström; Johan Wiström; Tor Monsen; Anders Sjöstedt; Bo Söderquist; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; staphylococcus epidermidis; staphylococcus saprophyticus; electrophoresis; gel; pulsed-field; genetic diversity; methicillin-resistance; UTI; drug resistance; multiple; bacterial; epidemiology; molecular; cross infection; molecular sequence data; Medical microbiology; Medicinsk mikrobiologi; Clinical bacteriology; Klinisk bakteriologi; Infectious diseases; Infektionssjukdomar; Clinical Bacteriology; klinisk bakteriologi; mikrobiologi; Microbiology; Infectious Diseases; infektionssjukdomar;

    Sammanfattning : Background Coagulase-negative staphylococci (CoNS) and in particular Staphylococcus epidermidis have emerged as major pathogens primarily causing nosocomial infections in patients with indwelling medical devices. These infections are often caused by multidrug-resistant strains of S. epidermidis (MDRSE). LÄS MER

  3. 2. Evolutionary Dynamics of Mutation and Gene Transfer in Bacteria

    Författare :Peter A Lind; Dan I Andersson; J. Arjan G. M. de Visser; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fitness cost; bacterial evolution; gene amplification; mutational biases; GC content; synonymous substitutions; horizontal gene transfer; experimental evolution; Bacteriology; Bakteriologi; Microbiology; Mikrobiologi; Genetics; Genetik; Biology; Biologi; Mikrobiologi; Microbiology;

    Sammanfattning : The study of bacterial evolution is fundamental for addressing current problems of antibiotic resistance and emerging infectious diseases and lays a solid foundation for successful and rational design in biotechnology and synthetic biology. The main aim of this thesis is to test evolutionary hypotheses, largely based on theoretical considerations and sequence analysis, by designing scenarios in a laboratory setting to obtain experimental data. LÄS MER

  4. 3. Antibiotic Resistance and Population Dynamics of Escherichia coli in Relation to a Large Scale Antibiotic Consumption Intervention

    Författare :Martin Sundqvist; Otto Cars; Gunnar Kahlmeter; Dan I Andersson; Jordi Vila; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reversibility; trimethoprim; dfr; associated resistance; MLST; Infectious diseases; Infektionssjukdomar; Clinical bacteriology; Klinisk bakteriologi; Medical microbiology; Medicinsk mikrobiologi; Infectious Diseases; Infektionssjukdomar;

    Sammanfattning : Antibiotic resistance challenges the practice and development of modern medicine. The aim of this thesis was to test the hypothesis that antibiotic resistance is reversible once the selection pressure of an antibiotic is removed. LÄS MER

  5. 4. Studies on hereditary C2 deficiency: Frequent occurrence of severe infections, atherosclerosis and rheumatological manifestations

    Författare :Göran Jönsson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; mykologi; bakteriologi; virologi; Mikrobiologi; mycology; Complement; Complement C2 deficiency; Infectious diseases; Atherosclerosis; SLE; Autoantibodies; GM allotypes; Immunodeficiency state; Medicine human and vertebrates ; Medicin människa och djur ; Microbiology; virology; bacteriology; Immunologi; serologi; Infections; Infektioner;

    Sammanfattning : The complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. LÄS MER

  7. 5. Identification and Characterization of Biomarkers in Bacterial Infections

    Författare :Martin Storm; Lars Engstrand; Ann-Christine Syvänen; Hans-Jurg Monstein; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Microbiology; Bacteriology; Chlamydia trachomatis; Bordetella perussis; Helicobacter pylori; Real-Time PCR; Microarray; Antigenome; Vaccine; Biomarker; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Sammanfattning : In recent years molecular biology has become an integral part of the clinical laboratory. With an ever increasing number of methodologies and applications being presented each year it has increased our knowledge of how bacteria cause disease as well as our ability to predict disease outcome. LÄS MER