Sökning: "infectious diseases Infectious diseases"
Visar resultat 11 - 15 av 437 avhandlingar innehållade orden infectious diseases Infectious diseases.
11. Antibiotic Resistance and Population Dynamics of Escherichia coli in Relation to a Large Scale Antibiotic Consumption Intervention
Sammanfattning : Antibiotic resistance challenges the practice and development of modern medicine. The aim of this thesis was to test the hypothesis that antibiotic resistance is reversible once the selection pressure of an antibiotic is removed. LÄS MER
12. Molecular epidemiology of coagulase-negative staphylococci in hospitals and in the community
Sammanfattning : Background Coagulase-negative staphylococci (CoNS) and in particular Staphylococcus epidermidis have emerged as major pathogens primarily causing nosocomial infections in patients with indwelling medical devices. These infections are often caused by multidrug-resistant strains of S. epidermidis (MDRSE). LÄS MER
13. Implications of Local Puumala Hantavirus Genetics and Epidemiology for Diagnostics and Vaccine Development
Sammanfattning : Puumala viruses, a member of the Hantavirus genus in the Bunyaviridae family, are enveloped by a lipid bilayer and possesses a tripartite single stranded RNA genome with negative polarity. The hantaviruses encode four proteins: a nucleocapsid protein (N), two membrane spanning glycoproteins (GN and GC) and a RNA dependent RNA polymerase (RdRp). LÄS MER
14. C5a Receptor Expression in Severe Sepsis and Septic Shock
Sammanfattning : In patients with sepsis, the activation of the cascade systems, for example the complement system with the generation of C5a, is followed by a state of immunosuppression with impaired bactericidal capacity caused by suppression of the neutrophil granulocytes. To inhibit the C5a-induced systemic inflammatory and the following anti-inflammatory responses, different anti-C5a strategies have been successful in experimental models of sepsis. LÄS MER
15. Antibiotic-induced Bacterial Toxin Release – Inhibition by Protein Synthesis Inhibitors
Sammanfattning : Toxic products, such as endotoxin from the gram-negative and exotoxin from the gram-positive bacteria, are the most important initiators of the inflammatory host response in sepsis. In addition to antibacterial treatment, numerous attempts have been made to interfere with the exaggerated proinflammatory cascade initiated by the toxins. LÄS MER