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1. 1. Chlamydia pneumoniae in Aortic Valve Sclerosis and Thoracic Aortic Disease : Aspects of Pathogenesis and Therapy

   Författare :Christina Nyström-Rosander; Kenneth Persson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; Chlamydia pneumoniae; aortic valve sclerosis; trace elements; thoracic aorta; antibiotics; Polymerase Chain Reaction PCR ; electron microscopy EM ; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar; infektionssjukdomar; Infectious Diseases;

   Sammanfattning : The obligate intracellular bacterium Chlamydia pneumoniae (Cp), a common human pathogen, has been associated with atherosclerotic cardiovascular disease. The aetiology of non-rheumatic aortic valve sclerosis has, however, not been clarified. LÄS MER

3. 2. Rickettsia helvetica; Detection in arthropods and human tissues and its relation to clinical disease

   Författare :Kenneth Nilsson; Björn Olsen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; rickettsia; spotted fever; tick; PCR; myocarditis; sarcoidois; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar; Infektionssjukdomar; Infectious Diseases;

   Sammanfattning : A relation between R. helvetica and perimyocarditis was, in two young men who died of sudden cardiac death during exercise in 1997, suggested by a seminested PCR, for three different genes, sequencing of the amplified products, documentation of a seroresponse and histopathologic changes in accordance with rickettsioses. LÄS MER

4. 3. Epidemiology of Enterococci with Acquired Resistance to Antibiotics in Sweden : Special emphasis on Ampicillin and Vancomycin

   Författare :Erik Torell; Mats Kallin; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; Antimicrobial resistance; enterococci; epidemiology in Sweden; intra-hospital spread; shedding; risk-factors; infection; colonization; virulence factors; ARE; VRE; Php; PFGE; esp; gyrA; parC; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar; infektionssjukdomar; Infectious Diseases;

   Sammanfattning : The first hospital outbreak of vancomycin-resistant enterococci (VRE) and carriage rates of VRE and ampicillin-resistant enterococci (ARE) in Sweden were investigated. Clonal relationships and mutations in fluoroquinolone resistance determining regions among ARE collected nation-wide were studied. LÄS MER

5. 4. Serum Amyloid A Protein (SAA) in Healthy and Infected Individuals

   Författare :Anders Lannergård; Göran Friman; Anders Larsson; Uwe Ewald; Jonas Hedlund; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; acute phase proteins; adult; Administration Oral; aminoglycosides; amyloidosis; antibiotics; bacterial infections; body temperature; C-reactive protein; cefuroxime; cystitis; cytokines; elderly; infant; interleukin-6; newborn; pyelonephritis; serum amyloid A protein; virus diseases; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar;

   Sammanfattning : Serum amyloid A protein (SAA) is an acute phase protein that has recently gained increasing interest as a potential marker for disease and treatment monitoring. We investigated SAA and CRP levels in (a) patients with various common infectious diseases (n=98), (b) patients with pyelonephritis (n=37) versus patients with cystitis (n=32), (c) healthy individuals of varying ages (n=231), (d) very immature newborn infants with or without nosocomial infections (NIs) (n=72) and (e) patients with bacterial infections treated with cefuroxime (n=81). LÄS MER

7. 5. Biochemical and structural studies of proteins supporting the genome replication of enteroviruses and Giardia intestinalis

   Författare :Kasturika Shankar; Lars-Anders Carlson; Daniel Hurdiss; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Structural Biology; Membrane reconstitution; Infectious diseases; Virus; Protozoa; Infectious Diseases; infektionssjukdomar; medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : The Enterovirus genus of the Picornaviridae family includes non-enveloped, positive-sense single-stranded RNA (ssRNA) viruses. This genus of viruses causes many diseases such as poliomyelitis by poliovirus (PV), cardiomyopathy by coxsackievirus B3 (CVB3), common cold by rhinoviruses (RVs) and meningitis by Enterovirus 71 (EV 71). The 7. LÄS MER