Sökning: "infectious diseases Immunology"

Visar resultat 11 - 15 av 46 avhandlingar innehållade orden infectious diseases Immunology.

  1. 11. Macrophage programming and host responses to bacterial infection

    Författare :Xiao Wang; Hong Sjölinder; Martin Rottenberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Macrophages; meningococci; mycobacteria; NhhA; CD46; cytokines; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Macrophages are dynamic, plastic, and heterogeneous immune cells that play an important role in host immune defense against bacterial infection. Various bacterial pathogens, such as Neisseria meningitidis and Mycobacterium tuberculosis, can modulate host immune responses by interfering with macrophage differentiation and polarization. LÄS MER

  3. 12. Design, production and characterization of synthetic immunogens : application on Plasmodium falciparum malaria antigens

    Författare :Anders Sjölander; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The development of synthetic subunit vaccines is presently one of the major strategies to construct vaccines against infectious diseases. Such vaccines are based on isolated and characterized immunogens and should include appropriate B- and T-cell epitopes. LÄS MER

  4. 13. Tularemia : epidemiological, clinical and diagnostic aspects

    Författare :Henrik Eliasson; Erik Bäck; Anders Sjöstedt; Clas Ahlm; Örebro universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Francisella; tularemia; epidemiology; case-control; diagnosis; PCR; clinical characteristics; immunology; ELISA; lymphocyte stimulation; Medicine; Medicin; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : Tularemia is a zoonosis caused by the small, fastidious, gram-negative rod Francisella tularensis that appears over almost the entire Northern Hemisphere. In Sweden, tularemia has appeared mainly in restricted areas in northern parts of central Sweden. LÄS MER

  5. 14. Persistent infection by Yersinia pseudotuberculosis

    Författare :Kemal Avican; Maria Fällman; Wyndham W. Lathem; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Persistent infection; RNA-seq; PMNs; Yersinia; Transcriptome; wrba; fnr; rovA; arcA; rfaH; molekylärbiologi; Molecular Biology; Infectious Diseases; infektionssjukdomar; immunologi; Immunology;

    Sammanfattning : Enteropathogenic Yersinia species can infect many mammalian organs such as the small intestine, cecum, Peyer’s patches, liver, spleen, and lung and cause diseases that resemble a typhoid-like syndrome, as seen for other enteropathogens. We found that sublethal infection doses of Y. LÄS MER

  7. 15. Determining the role of guanylate-binding proteins for host defense against Francisella tularensis

    Författare :Nasibeh Mohammadi; Anders Sjöstedt; Wolfgang P. Schröder; Anetta S. Härtlova; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; Guanylate-binding proteins; bone marrow-derived macrophages; IFN-γ activation; cytokine patterns; inflammasome pathways; co-infection; mouse co-culture model; Biochemistry; biokemi; immunologi; Immunology; mikrobiologi; Microbiology; molekylärbiologi; Molecular Biology; Infectious Diseases; infektionssjukdomar;

    Sammanfattning : Francisella tularensis is a highly virulent, intracellular bacterium and the causative agent of the human disease tularemia. This is a zoonotic, often vector-borne disease. Due to its intracellular nature, F. LÄS MER