Sökning: "infectious diseases Immunology Immunogenetics"

Hittade 1 avhandling innehållade orden infectious diseases Immunology Immunogenetics.

  1. 1. The genetic basis of T and B cell contribution to autoimmune diabetes in NOD mice

    Detta är en avhandling från Umeå : Medicinsk biovetenskap

    Författare :Vinícius Motta; Umeå universitet.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 Diabetes; NOD mouse; CTLA-4; superantigen; T cells; Idd; marginal zone B cells; embryo aggregation chimera; negative selection; MEDICINE Microbiology; immunology; infectious diseases Immunology Immunogenetics; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi Immungenetik;

    Sammanfattning : The nonobese diabetic mouse (NOD) is an excellent animal model to study type 1 diabetes. As with some humans, disease in the NOD mouse is effected by a combination of genetic and environmental factors. At least 20 insulin dependent diabetes (Idd) susceptibility loci have been identified so far, both in humans and in the NOD mouse. LÄS MER