Sökning: "infection reactivation"

Visar resultat 6 - 10 av 35 avhandlingar innehållade orden infection reactivation.

  1. 6. Herpesvirus Infection and Immunity in Neurocognitive Disorders

    Författare :Gabriel Westman; Britt-Marie Eriksson; Martin Ingelsson; Olle Korsgren; Jan Ernerudh; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Herpes simplex encephalitis; Herpesvirus; Cytomegalovirus; CMV; HSV-1; HHV-6; CD8 T-cells; Cellular immunity; Immunosenescence; Autoimmunity; NMDA receptor; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Herpesviruses have co-speciated with several vertebrate and invertebrate animals throughout the history of evolution. In the immunocompetent human host, primary infection is usually benign, whereafter the virus is brought into life-long latency. LÄS MER

  3. 7. Cytomegalovirus infection in vascular diseases and transplant rejection

    Författare :Mensur Dzabic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human cytomegalovirus (HCMV) infects 60-100% of the adult population. It belongs to the Herpesviridae family and establishes latency within its host post primary infection. HCMV reactivation is dependent on inflammation and the virus has evolved numerous mechanisms to sustain an inflammatory process and thus prolong its replication period. LÄS MER

  4. 8. Biological importance of cytomegalovirus infection in health and disease : profound effects of infection on monocyte and smooth muscle cell function

    Författare :Sara Gredmark; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cytomegalovirus; monocyte macrophage; dendritic cell; cellular differentiation; latency; atherosclerosis; smooth muscle cells;

    Sammanfattning : Human cytomegalovirus (HCMV) is a herpesvirus. Following a primary infection, HCMV persists in the body in a latent form and most adults are virus carriers. Infection and reactivation of HCMV occur in inummocompromised patients causing severe disease and appear to be the result of inflammatory processes. LÄS MER

  5. 9. Control of Epstein-Barr virus infection by cytotoxic T lymphocytes

    Författare :Pedro-Otavio de Campos-Lima; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Epstein-Barr virus; Cytotoxic T lymphocytes; T cell receptor; CTLescape mutants;

    Sammanfattning : Cytotoxic T lymphocytes (CTL) play a critical role in response to Epstein-Barr virus (EBV), a widespread human herpes virus that persists in healthy carriers as a latent infection of B cells and is implicated in the pathogenesis of lymphoid and epithelial cell malignancies. Six virus encoded nuclear antigens, EBNA1-6, and three membrane proteins, LMP1, -2A and -2B, are regularly detected in EBV transformed lymphoblastoid cell lines (LCLs). LÄS MER

  7. 10. Early diagnosis of cytomegalovirus infection using monoclonal antibodies and DNA amplification

    Författare :Benita Zweygberg Wirgart; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :cytomegalovirus; monoclonal antibodies; polymerase chain reaction; CMV early antigen; CMV pp65antigen.;

    Sammanfattning : Human cytomegalovirus (HCMV) is ubiquitous and frequently infects normal individuals with few serious clinical consequences. However, patients with impaired cellular immunity frequently develop life-threatening opportunistic HCMV infections due to either primary infection or reactivation of latent virus. LÄS MER