Sökning: "infection reactivation"
Visar resultat 21 - 25 av 35 avhandlingar innehållade orden infection reactivation.
21. Improving immunogenicity of hepatitis B and C viral proteins for vaccine design
Sammanfattning : The hepatitis B and C virus (HBV, HCV) both presents a global health challenge, with an estimated 350 million individuals chronically infected with HBV and over 200 million infected with HCV. Reported cases of HBV and HCV have declined significantly due to screening of blood products and the availability of HBV vaccination. LÄS MER
22. The effect of human cytomegalovirus on innate immune responses : immune activation and evasion
Sammanfattning : Human cytomegalovirus (HCMV) is a wide-spread virus infecting about 60-90 % of the healthy human population. After a primary infection, the virus establishes life-long latency in its host. LÄS MER
23. HCMV-induced epigenetic alterations : a novel pathway to CNS tumors?
Sammanfattning : Aberrant DNA hypermethylation at CpG islands is a well-established phenomenon involved in transcriptional silencing of tumor suppressor genes. CpG island hypomethylation-mediated reactivation of oncogenes is also documented in several cancer types. LÄS MER
24. The transcriptomic landscape of Epstein-Barr virus associated tumors at cellular and single-molecule level
Sammanfattning : Epstein-Barr virus (EBV) was the first oncovirus found in humans. Almost all adults worldwide are asymptomatic carriers of EBV. The latent EBV-infection malignifies in approximately 200,000 individuals each year. LÄS MER
25. An epidemiological study on nasopharyngeal carcinoma
Sammanfattning : Nasopharyngeal carcinoma (NPC) is a malignancy known for its unique geographic and ethnic distribution characterized by particularly high incidence in southern China, Southeast Asia, and North and East Africa, but being rare in the rest of the world. Its etiology has remained enigmatic and the accumulated evidence suggests that genetic predisposition, environmental factors, and infection with Epstein-Barr virus (EBV) are involved. LÄS MER