Sökning: "individualized treatments"

Visar resultat 1 - 5 av 29 avhandlingar innehållade orden individualized treatments.

1. 1. Development of individualized surgical treatments for malignant melanoma

   Författare :Valerio Belgrano; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanoma; sentinel node; isolated limb perfusion; immune-humanized xenograft mouse models; translational research;

   Sammanfattning : Background: Cutaneous melanoma is a malignancy with an increasing incidence worldwide, especially in northern Europe. The aim of this thesis is to scrutinize the results achieved by traditional surgery and the opportunities offered by translational research for the more advanced stages of the disease. LÄS MER

3. 2. Philosophical Issues in Medical Intervention Research

   Författare :Jesper Jerkert; Sven Ove Hansson; Tor Sandqvist; John Cantwell; Nils-Eric Sahlin; KTH; []
   Nyckelord :HUMANIORA; HUMANITIES; scientific method; study design; methodology; alternative medicine; medical research; individualized treatments; eligibility; confounders; evidence; evidence-based medicine; mechanistic reasoning; hierarchy of evidence; Filosofi; Philosophy;

   Sammanfattning : The thesis consists of an introduction and two papers. In the introduction a brief historical survey of empirical investigations into the effectiveness of medicinal interventions is given. Also, the main ideas of the EBM (evidence-based medicine) movement are presented. LÄS MER

4. 3. Treating depression and its comorbidity : From individualized Internet-delivered cognitive behavior therapy to affect-focused psychodynamic psychotherapy

   Författare :Robert Johansson; Gerhard Andersson; Per Carlbring; Pim Cuijpers; Jacques Barber; Linköpings universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Depression; comorbidity; psychological treatment; psychotherapy; Internet; Internet-delivered treatment; cognitive behavior therapy; psychodynamic psychotherapy; Depression; komorbiditet; psykologisk behandling; psykoterapi; Internet; internetbaserad behandling; kognitiv beteendeterapi; psykodynamisk psykoterapi;

   Sammanfattning : The overarching goal of this thesis has been to enhance Internet-delivered psychological treatments for depression and its comorbidity. To this end, three randomized controlled trials (Study II, III and IV) with a total of 313 participants were conducted. LÄS MER

5. 4. Identification of new disease mechanisms and treatments for type 2 diabetes based on genetic variants and gene expression networks

   Författare :Annika Axelsson; Diabetes - öpatofysiologi; []
   Nyckelord :Type 2 diabetes; insulin; ADRA2A; genotype; gene network analysis; SOX5; drug repositioning; sulforaphane; clinical study; typ 2-diabetes; insulin; ADRA2A; genotyp; gennätverksanalys; SOX5; sulforafan; klinisk studie;

   Sammanfattning : Improved understanding of the disease mechanisms underlying type 2 diabetes (T2D) is needed, and so are new treatments.A new T2D risk variant was recently identified in ADRA2A, which encodes the α2A-adrenergic receptor. LÄS MER

7. 5. Physical activity on prescription : studies on physical activity level, adherence and cardiovascular risk factors

   Författare :Lena Kallings; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Physical activity; exercise; counseling; patient-centered; public health; health promotion; life style; primary health care; health services; intervention studies; health behaviour;

   Sammanfattning : Physical activity is one of the most important public health determinants, and the health care sector is highlighted as a central setting in the promotion of physical activity in the population as well as at an individual level. One method that has attracted attention over recent years, is physical activity prescribed by doctors or other health care professionals, even though there is insufficient evidence to determine that any method of promoting physical activity in the health care setting is superior to another. LÄS MER