Sökning: "individual patient data meta-analysis"
Visar resultat 1 - 5 av 10 avhandlingar innehållade orden individual patient data meta-analysis.
1. International Outcomes of Total Hip Arthroplasty: Influence of Patient, Implant, and Surgical factors on Total Hip Arthroplasty Survivorship in Sweden, the US, and Australia
Sammanfattning : Abstract Background Hip osteoarthritis (OA) is debilitating disease resulting in pain, stiffness, and reduced physical function. Although total hip arthroplasty (THA) is a successful treatment for OA, some THAs require revision surgery due to infection, dislocation, aseptic loosening, fracture and other reasons. LÄS MER
2. Effect of antihypertensive treatment at different blood pressure levels
Sammanfattning : BackgroundHigh blood pressure is associated with an increased risk of cardiovascular disease and premature death. The shape of association between blood pressure and the risk of cardiovascular events is debated. Some researchers suggest that the association is linear or log-linear, whereas others suggest it is J-shaped. LÄS MER
3. Negative effects of Internet-based cognitive behavior therapy : Monitoring and reporting deterioration and adverse and unwanted events
Sammanfattning : Internet-based cognitive behavior therapy (ICBT) has the potential of providing many patients with an effective form of psychological treatment. However, despite helping to improve mental health and well-being, far from everyone seem to benefit. In some cases, negative effects may also emerge. LÄS MER
4. Testing the boundaries for expectation effects in health and disease
Sammanfattning : Expectations affect our physiology and clinical outcomes, however the boundaries for this modulation are poorly understood. The purpose of this thesis is to investigate minimal requirements to elicit expectation effects on health-related outcomes, using experiments and an independent patient data meta-analysis. LÄS MER
5. Major determinants of outcome and dosing in warfarin treatment
Sammanfattning : The aim of this thesis was to identify factors that determine individual patients sensitivity to the anticoagulant warfarin, and to quantify the effect of such factors on different measures of anticoagulation control. As part of this project, a large bio-bank was prospectively collected, with DNA and clinical data from more than 1500 patients starting warfarin treatment (the WARG cohort). LÄS MER