Sökning: "in-vitro testing"
Visar resultat 21 - 25 av 165 avhandlingar innehållade orden in-vitro testing.
21. Chemosensitivity in Breast Cancer
Sammanfattning : Breast cancer mortality in Sweden is now in decline, thanks to early detection and the wide use of adjuvant endocrine therapy and chemotherapy. While hormone receptor status is predictive of response to endocrine treatment, there is no clinically useful predictive marker of a patient’s response to chemotherapy. LÄS MER
22. Premixed Acidic Calcium Phosphate Cements
Sammanfattning : Calcium phosphate cements are used in medicine to fill bone defects or give support to screws and plates in fracture fixation. The cements are formed via mixing a powder with water and the mixture harden through a dissolution-precipitation reaction. LÄS MER
23. Effects of gold- and silver nanoparticles on the retina
Sammanfattning : Over the past decade, a massive increase in the use of nanomaterials and nanoparticles (NPs) in both commercial and medical applications has occurred. Medical applications include advanced drug delivery vehicles, imaging and hyper thermic therapies. LÄS MER
24. Integrating Efficacy and Toxicity in Preclinical Anticancer Drug Development : Methods and Applications
Sammanfattning : Preclinical testing is an important part of cancer drug development. The aim of this thesis was to establish and evaluate preclinical in vitro methods useful in the development of new anticancer drugs. In paper I, the development of non-clonogenic assays (FMCA-GM) using CD34+ stem cells for assessment of haematological toxicity was described. LÄS MER
25. On the structure and mechanical properties of in vitro salivary pellicles
Sammanfattning : Salivary pellicles display exceptional hydration and lubrication performance. At present, there are still gaps in the understanding of how this is achieved. LÄS MER