Sökning: "in-situ cell"

Visar resultat 11 - 15 av 550 avhandlingar innehållade orden in-situ cell.

1. 11. Improvements and Applications of in situ Proximity Ligation Assays

   Författare :Karin Grannas; Ola Söderberg; Christer Wingren; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molekylär medicin; Molecular Medicine;

   Sammanfattning : The cells building up the human body is in constant communication with each other. This communication is done through large complex networks of signaling pathways for inter- and intracellular signal transduction. The signaling activity regulates many important processes, for example cell death, proliferation and differentiation. LÄS MER

3. 12. Making Visible the Proximity Between Proteins

   Författare :Carl-Magnus Clausson; Ola Söderberg; Jens Coorssen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Proximity ligation assay; In situ PLA; rolling circle amplification; protein interaction; protein-protein interaction; in situ; single cell; single molecule; protein complex; antibody; cancer; tissue section; microscopy; image analysis; system biology; multiplex; dynamic range; methods development; systems biology; Molekylär medicin; Molecular Medicine;

   Sammanfattning : Genomic DNA is the template of life - the entity which is characterized by a self-sustaining anatomical development, regulated signaling processes, the ability to reproduce and to respond to stimuli. Through what is classically known as the central dogma, the genome is transcribed into mRNA, which in turn is translated into proteins. LÄS MER

4. 13. Application of Padlock Probe Based Nucleic Acid Analysis In Situ

   Författare :Sara Henriksson; Mats Nilsson; Ulf Landegren; Harvest Gu; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Padlock probe; rolling circle amplification; single cell gel electrophoresis assay; comet assay; Crimean Congo hemorrhagic fever virus; Molecular medicine; Molekylär medicin; Molekylär medicin; Molecular Medicine;

   Sammanfattning : The great variation displayed by nucleic acid molecules in human cells, and the continuous discovery of their impact on life, consequently require continuous refinements of molecular analysis techniques. Padlock probes and rolling circle amplification offer single nucleotide discrimination in situ, a high signal-to-noise ratio and localized detection within cells and tissues. LÄS MER

5. 14. Development of Novel In Situ ESEM Techniques for the Study of Water Interaction with Soft Materials

   Författare :Anna Jansson; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; environmental scanning electron microscopy; cellulose fibre; water transport; swelling; osmotic shock; yeast cell; in situ; manipulator; water interaction;

   Sammanfattning : The transport of water is central to many applications of soft biomaterials; for example water management in personal care products, controlled drug release in pharmaceuticals and, on a fundamental level, the activities of living cells. Water transport through a material may occur in both liquid and gas phase, and is highly dependent on the microstructure. LÄS MER

7. 15. Development of Novel In Situ Microscopy Techniques for the Study of Water Interaction with Soft Materials

   Författare :Anna Jansson; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; environmental scanning electron microscopy; polymer film; manipulator; yeast cell; swelling; in situ; water transport; cellulose fibre; osmotic shock; water interaction;

   Sammanfattning : The transport of water in soft materials can occur in liquid or gas phase and is highly dependent on the material microstructure and the structure dynamics. Understanding these relationships is the basis for the development of predictive models that can aid the design of new and improved functional materials. LÄS MER