Sökning: "in vivo test"

Visar resultat 6 - 10 av 251 avhandlingar innehållade orden in vivo test.

  1. 6. Mechanisms of Osseointegration: Experimental Studies on Early Cellular and Molecular Events in vivo

    Författare :Omar Omar; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Osseointegration; titanium; bone; gene expression; bone-implant interface; qPCR; inflammation; cytokine; chemotaxis; chemokine; integrin; bone formation; remodeling; in vivo; rat; immunohistochemistry; ultrastructure; biomechanical torque test;

    Sammanfattning : The early cellular and molecular activities determining the early tissue response and bone formation at bone/implant interface are not fully understood. The general aim of the current thesis was to develop a model for studying the early molecular and cellular activities in different bone types, and in response to different implant surface properties. LÄS MER

  3. 7. In Vitro – In Vivo Correlation of Injectable Lipid Formulations

    Författare :Lars Söderberg; Livsmedelsteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; EC 50; erythrocyte; human plasma; lipid injectable formulation; IVIVC; fatty acid; in vitro release; Peripheral nerve block; neurolytic; structure-activity;

    Sammanfattning : In order to develop new pharmaceuticals, to optimize pharmacotherapy and secure patient safety, documentation of the properties of pharmaceutical formulations is a most important process. A significant practical problem associated with pre-clinical evaluation of lipophilic substances with pharmacological properties is their low aqueous solubility. LÄS MER

  4. 8. Cytokine responses in metal-induced allergic contact dermatitis : Relationship to in vivo responses and implication for in vitro diagnosis

    Författare :Jacob Minang; Marita Troye-Blomberg; Niklas Ahlborg; Rik Scheper; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metal allergy; Contact dermatitis; cytokines; ELISA; ELISpot; Flow cytometry; Immunology; Immunologi;

    Sammanfattning : Transition metals such as nickel (Ni), cobalt (Co), palladium (Pd), chromium (Cr) and gold (Au) are widely used as alloys in jewelry and biomaterials such as orthodontic and orthopaedic appliances. These metals also cause cell-mediated allergic contact dermatitis (ACD) reactions in a significant proportion of the population upon prolonged direct exposure. LÄS MER

  5. 9. Urinary tract infections in pregnancy : studies in vivo and in vitro

    Författare :Musa Sekikubo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The risk of urinary tract infection (UTI) in pregnant women is increased and predisposes them to acute pyelonephritis together with poor pregnancy outcomes. Increased frequency of micturition, nocturia and lower abdominal discomfort are common non-specific complaints during pregnancy, which render clinical diagnosis of UTI inaccurate. LÄS MER

  7. 10. Hemocompatibility of materials for use in prosthetic heart valves

    Författare :Yanqi Yang; Eric G. Butchart; Linköpings universitet; []
    Nyckelord :Heart valve prosthesis; mechanical heart valves; bioprosthetic heart valves; biomaterials; hemocompatibility; blood-material interaction; in vivo test; MEDICINE; MEDICIN;

    Sammanfattning : Thromboembolism (valve thrombosis and systemic embolism) is the main drawback of mechanical heart valve prostheses. The patients carrying these valves have to be subjected to life-long anticoagulant therapy to reduce thromboembolism. LÄS MER