Sökning: "in vivo reconstitution"

Visar resultat 1 - 5 av 27 avhandlingar innehållade orden in vivo reconstitution.

1. 1. Hematopoietic stem cells: c-mpl and TNF receptor function

   Författare :Veslemøy Ramsfjell; Avdelningen för molekylärmedicin och genterapi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumor necrosis factor-a.; in vivo reconstitution; ex vivo expansion; long-term bone marrow culture; differentiation; proliferation; synergy; Hematopoietic stem cells; thrombopoietin; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

   Sammanfattning : Hematopoietic stem cells (HSC) are crucial to life. Daily and throughout the life span of an individual they are responsible for replacing approximately 10(12) mature blood cells. Mature cells are, for example, required for transportation of oxygen, defense against infections and to stop bleeding. LÄS MER

3. 2. Hox transcription factors in hematopoiesis

   Författare :Jon Mar Björnsson; Avdelningen för molekylärmedicin och genterapi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Hematologi; extracellulära vätskor; Haematology; hematopoies; tet; Hox; cre lox;

   Sammanfattning : Hematopoiesis is a lifelong, dynamic process in which a small number of pluripotent hematopoietic stem cells (HSC) residing in the bone marrow (BM) give rise to billions of mature blood cells of both myeloid and lymphoid origin each day. This enormous capacity of HSC has been utilized in BM transplantations for 4 decades and is also very important for future gene therapy. LÄS MER

4. 3. Membrane-mimetic systems : Novel methods and results from studies of respiratory enzymes

   Författare :Gustav Nordlund; Peter Brzezinski; Joachim Heberle; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lipids; membrane proteins; method development; respiration; reconstitution; supported membranes; SNAREs; liposome fusion; lipid-protein interactions; Biochemistry; biokemi;

   Sammanfattning : The processes localized to biological membranes are of great interest, both from a scientific and pharmaceutical point of view. Understanding aspects such as the detailed mechanism and regulation of these processes requires investigation of the structure and function of the membrane-bound proteins in which they take place. LÄS MER

5. 4. New approaches in biomembrane chromatomatography and microchromatographic techniques

   Författare :Cheng-Ming Zeng; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; biokemi; Biochemistry;

   Sammanfattning : Development of methods for rendering chromatography more applicable to studies in lifesciences remains an area of active research. In the present work, new methods inbiomembrane chromatography and microchromatographic techniques have been developedand applied successfully to quantitative analysis of biological interactions and separations ofproteins on a micro-scale. LÄS MER

7. 5. Immunological aspects of maternal-foetal interactions in mice

   Författare :Marie Arvola; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Neonatal mice; milk; placenta; fetal rejection; IgG; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Developmental Biology; miljömedicinsk utvecklingsbiologi;

   Sammanfattning : Mammalian pregnancy is an immunological paradox. The foetus, which expresses both paternal and maternal cell-surface molecules, has to be protected from rejection by the maternal immune system. At the same time, the mother has to have an efficient immune defence and must provide her offspring with antibodies. LÄS MER