Sökning: "in vitro tests"

Visar resultat 1 - 5 av 117 avhandlingar innehållade orden in vitro tests.

  1. 1. Acetylcholine in Spinal Pain Modulation : An in vivo Study in the Rat

    Författare :Klas Abelson; Urban Höglund; Ernst Brodin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Laboratory animals; Pain; Nociception; Antinociception; Acetylcholine; Muscarinic; Nicotinic; Spinal cord; Microdialysis; Försöksdjursvetenskap; Laboratory animal science; Försöksdjursvetenskap;

    Sammanfattning : The spinal cord is an important component in the processing and modulation of painful stimuli. Nerve signals from the periphery are relayed and further conducted to the brain (nociception) in the spinal cord, and the most essential modulation of painful information (antinociception) occurs here. LÄS MER

  3. 2. Dendritic cells in allergy In vitro models for studies of the human immune response

    Författare :Kristina Larsson; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; vaccine; Th2; transcriptional profiling; T cell; nanosphere; Immunologi; MUTZ-3; microarray; in vitro model; Allergic rhinitis; dendritic cell; serologi;

    Sammanfattning : This thesis, which is based on four original papers, deals with human dendritic cells (DCs) in immunity and allergy. DCs play a key role in the regulation of immune responses by acting as the sentinels of the immune system, specialized in the uptake of a diverse range of antigens. LÄS MER

  4. 3. Comparative in vivo and in vitro studies on the biomechanics of maxillary partial dentures. A methodological and experimental study

    Författare :Cláudio Pinheiro Fernandes; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stomatology; biomechanics; Bite force; conical crowns; denture design; in vitro; in vivo; photoelasticity; strain gauges; Odontology; stress analysis.; Odontologi;

    Sammanfattning : Biomechanical aspects are generally agreed to be significant, particularly during the planning of restorative treatments and the design of prosthetic appliances. However, comparative in vivo/in vitro studies show wide differences in the magnitudes and patterns of functional strains in prosthetic devices. LÄS MER

  5. 4. Hazard screening of contaminated sites : bioavailable fractions and biological in vitro tools

    Författare :Daniel Ragnvaldsson; Mats Tysklind; Per Leffler; Lars Lövgren; Bengt-Erik Bengtsson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hazard screening; bioavailability; metal pollution; in vitro cytotoxicity; water extraction; CCA; arsenic genotoxicity; genotoxicity; Contaminated soil; Environmental chemistry; Miljökemi;

    Sammanfattning : The environmental bioavailability of contaminants, rather than their total concentrations in the soil compartment play a decisive role for the risks associated with contaminated sites. Various soil constituents and abiotic conditions have strong influence on bioavailability, which may vary substantially between different locations. LÄS MER

  7. 5. Computational methods for analyzing dioxin-like compounds and identifying potential aryl hydrocarbon receptor ligands : multivariate studies based on human and rodent in vitro data

    Författare :Malin Larsson; Patrik Andersson; Anna Linusson; Mats Tysklind; Scott Boyer; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; dioxin-like compounds; multivariate analysis; toxic equivalency factor; quantitative structure-activity relationship; descriptors; virtual screening; in vitro; species variation; aryl hydrocarbon receptor;

    Sammanfattning : Polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) are omnipresent and persistent environmental pollutants. In particular, 29 congeners are of special concern, and these are usually referred to as dioxin-like compounds (DLCs). LÄS MER