Sökning: "in vitro metabolism"

Visar resultat 6 - 10 av 427 avhandlingar innehållade orden in vitro metabolism.

1. 6. Blood flow and metabolism in the corpus luteum of the rat : in vivo and in vitro studies on the ovarian luteal and follicular compartment of the rat

   Författare :Mats Gåfvels; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ovary; follicle; corpus luteum; blood flow; metabolism; luteinizing hormone; noradrenaline; antidiuretic hormone;

   Sammanfattning : The ovary undergoes cyclic changes in follicular growth and luteogenesis due to the action of gonadotropins and steroids. The ovary and especially the corpus luteum has an exteremely high blood flow. There is a gap in our knowledge about the physiological role of the high blood flow of the corpus luteum. LÄS MER

3. 7. Systems and Synthetic Biology: ​“Mining human gut microbial metabolism through in vitro and in silico approaches”

   Författare :Promi Das; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gut; bile acids; metatranscriptomics; in vitro co-cultures; metagenomics; co-occurrence network; short chain fatty acids; metabolomics; metabolism; vitamins;

   Sammanfattning : The human gut microbiome is a consequence of mutual co-evolutionary interaction between the eukaryotic and prokaryotic parts of the mammalian holobiont. Based on the environmental and dietary inputs, there is a succession of microorganisms living inside the human colon. LÄS MER

4. 8. Metabolism of articular cartilage proteoglycans in vitro : effects of synovial membrane products and mechanical pressure

   Författare :Agneta Klämfeldt; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Articular cartilage; Proteoglycan metabolism; Synovial membrane products; Mechanical stress; Indom ethacin; Glucocorticoids; Prostaglandins; Osteoarthritis; Rheumatoid arthritis;

   Sammanfattning : The effect of synovial membrane products and mechanical pressure upon the metabolism of articular cartilage proteoglycans has been studied in vitro. The degradation of cartilage proteoglycans was studied in an organ culture system and measured as the release of [35S ] sulphate from prelabelled cartilage. LÄS MER

5. 9. Retinoic Acid Metabolism Blocking Agents and the Skin : In vivo and in vitro Studies of the Effects on Normal and Diseased Human Epidermis

   Författare :Elizabeth Pavez Loriè; Anders Vahlquist; Hans Törmä; Marie Virtanen; Helen Håkansson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP; CYP26; retinoids; vitamin A; RAMBA; metabolism; keratinocyte; epidermis; retinoid regulated genes; Dermatology and venerology; Dermatologi och venerologi;

   Sammanfattning : Retinoic Acid Metabolism Blocking Agents (RAMBAs) increase the endogenous levels of all-trans retinoic acid (RA) by inhibiting CYP26 enzymes. Thus they are believed to mimic the effects of retinoid treatment. Their mechanism of action and effects on vitamin A metabolism in keratinocytes are however uncertain. LÄS MER

7. 10. β-N-methylamino-L-alanine (BMAA)-induced neurotoxicity : Studies in vitro and in vivo

   Författare :Lisa Ersson; Malin Andersson; Eva B Brittebo; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; BMAA; neurotoxin; neurodegeneration; cellular transport; metabolic profiling; protein-association; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : β-N-methylamino-L-alanine (BMAA) is a neurotoxic non-proteinogenic amino acid produced naturally by cyanobacteria, diatoms and dinoflagellates and it has been detected in samples from fresh and marine water from all over the world. It can bioaccumulate in fish and shellfish, and has a potential to biomagnify in a terrestrial food chain. LÄS MER