Sökning: "in vitro degradation"
Visar resultat 1 - 5 av 251 avhandlingar innehållade orden in vitro degradation.
1. On magnesium-modified titanium coatings and magnesium alloys for oral orthopaedic applications : in vitro investigation
Sammanfattning : In dentistry and orthopaedic surgery, research to find and developimproved biomaterials is progressing rapidly.Of specific interest is to accelerate bone formation around theimplant surface, which could improve the reliability of the implanteven in patients with compromised situations. LÄS MER
2. Zopiclone degradation in biological samples : Characteristics and consequences in forensic toxicology
Sammanfattning : Bio-analytical results are influenced by in vivo factors such as genetics, pharmacological and physiological conditions and in vitro factors such as specimen composition, sample additives and storage conditions. Zopiclone (ZOP) is a short-acting hypnotic drug (Imovane®) used for treatment of insomnia. LÄS MER
3. Phosphatidylethanol - formation and degradation in blood and organs
Sammanfattning : Phosphatidylethanol (PEth) is an abnormal phospholipid formed exclusively by the action of phospholipase D (PLD) in the presence of ethanol. The degradation of PEth is slow and due to its accumulation in some cells the possibility to use PEth as marker of ethanol intake has been proposed. LÄS MER
4. In Vitro – In Vivo Correlation of Injectable Lipid Formulations
Sammanfattning : In order to develop new pharmaceuticals, to optimize pharmacotherapy and secure patient safety, documentation of the properties of pharmaceutical formulations is a most important process. A significant practical problem associated with pre-clinical evaluation of lipophilic substances with pharmacological properties is their low aqueous solubility. LÄS MER
5. Biodegradable gelatin microcarriers in tissue engineering : In vitro studies on cartilage and bone
Sammanfattning : Tissue engineering is a multidisciplinary field that combines cells, biomaterial scaffolds and environmental factors to achieve functional tissue repair. This thesis focuses on the use of macroporous gelatin microcarriers as scaffolds in tissue engineering applications, with a special focus on cartilage and bone formation by human adult cells in vitro. LÄS MER