Sökning: "impaired glucose tolerance"

Visar resultat 16 - 20 av 111 avhandlingar innehållade orden impaired glucose tolerance.

  1. 16. Islet glucose metabolism and insulin release in two animal models of glucose intolerance

    Författare :Zong-Chao Ling; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Goto-Kakizaki GK rat; transgenic mice; glucose-6-phosphatase activity; insulin secretion; glucocorticoids; [alpha]2-adrenergic receptors; hyperglycemia;

    Sammanfattning : Type 2 diabetes is a complex and heterogenous disease resulting from the interaction of defects of both genetic and environmental origin. Abnormalities contributing to the pathogenesis of type 2 diabetes include impaired [beta]-cell function, peripheral insulin resistance and increased hepatic glucose production. LÄS MER

  3. 17. Trends in obesity and type 2 diabetes : ethnic aspects and links to adipokines

    Författare :Mikael Lilja; Stefan Söderberg; Olov Rolandsson; Mats Eliasson; Kurt Svärdsudd; Umeå universitet; []
    Nyckelord :Type 2 diabetes; leptin; adiponectin; obesity; abdominal obesity; epidemiology; ethnicity; fasting glucose; post-load glucose; Family Medicine; allmänmedicin;

    Sammanfattning : Objective The prevalence of obesity and related diseases such as type 2 diabetes mellitus (T2DM) is increasing worldwide, and the Asian Indian population seems to be particularly susceptible to developing T2DM, even at a low body mass index (BMI). In Sweden, the age-adjusted prevalence of diabetes has not increased despite increasing self-reported obesity. LÄS MER

  4. 18. Genetic epidemiology of adiposity and abnormal glucose tolerance in South Asian Indians

    Författare :Senthil Kandaswamy Vasan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Genetic factors play a substantial role in susceptibility to common diseases such as type 2 diabetes (T2DM) and obesity-related disorders. The current investigation was undertaken to examine the association of genetic variants that indirectly affect diabetes-related traits through their effects on birth weight and adiposity in South Asian Indians. LÄS MER

  5. 19. Childhood Obesity and Islet Function

    Författare :Johan Staaf; Peter Bergsten; Anders Forslund; Hindrik Mulder; Uppsala universitet; []
    Nyckelord :type 2 diabetes mellitus; Uppsala Longitudinal Study of Childhood Obesity; palmitate; glucose-stimulated insulin secretion; hyperinsulinemia; hyperglucagonemia; GLP-1; glicentin; magnetic resonance imaging; metabolic syndrome; oral glucose tolerance test; centroid; Pediatrik; Pediatrics;

    Sammanfattning : The prevalence of childhood obesity and Type 2 Diabetes Mellitus (T2DM) has increased during recent decades. T2DM is accompanied with functional changes in the islets of Langerhans, which can be identified early in the pathogenesis. LÄS MER

  7. 20. Oral glucose tolerance test as a prognostic tool in patients with acute coronary syndrome

    Författare :Catarina Djupsjö; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Disturbances of glucose metabolism such as type 2 diabetes and impaired glucose tolerance are established risk factors for cardiovascular disease and mortality. The disturbances lead to hyperglycaemia and the most common methods to diagnose hyperglycaemia are HbA1c, oral glucose tolerance test (OGTT) and fasting plasma glucose (FPG). LÄS MER